1u6j

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[[Image:1u6j.gif|left|200px]]
[[Image:1u6j.gif|left|200px]]
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{{Structure
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<!--
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|PDB= 1u6j |SIZE=350|CAPTION= <scene name='initialview01'>1u6j</scene>, resolution 2.40&Aring;
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The line below this paragraph, containing "STRUCTURE_1u6j", creates the "Structure Box" on the page.
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|SITE=
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Methylenetetrahydromethanopterin_dehydrogenase Methylenetetrahydromethanopterin dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.99.9 1.5.99.9] </span>
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or leave the SCENE parameter empty for the default display.
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|GENE= mtd ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2320 Methanopyrus kandleri])
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|DOMAIN=
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{{STRUCTURE_1u6j| PDB=1u6j | SCENE= }}
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|RELATEDENTRY=[[1qv9|1qv9]]
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1u6j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u6j OCA], [http://www.ebi.ac.uk/pdbsum/1u6j PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1u6j RCSB]</span>
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}}
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'''The Structure of native coenzyme F420-dependent methylenetetrahydromethanopterin dehydrogenase at 2.4A resolution'''
'''The Structure of native coenzyme F420-dependent methylenetetrahydromethanopterin dehydrogenase at 2.4A resolution'''
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[[Category: Thauer, R K.]]
[[Category: Thauer, R K.]]
[[Category: Warkentin, E.]]
[[Category: Warkentin, E.]]
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[[Category: helix bundle]]
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[[Category: Helix bundle]]
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[[Category: monomer: alpha/beta domain]]
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[[Category: Monomer: alpha/beta domain]]
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[[Category: trimer of dimer]]
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[[Category: Trimer of dimer]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 10:49:06 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 00:06:01 2008''
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Revision as of 07:49, 3 May 2008

Image:1u6j.gif

Template:STRUCTURE 1u6j

The Structure of native coenzyme F420-dependent methylenetetrahydromethanopterin dehydrogenase at 2.4A resolution


Overview

The diffraction pattern of native protein crystals of F(420)-dependent methylenetetrahydromethanopterin dehydrogenase from Methanopyrus kandleri shows weak additional reflections compared with the selenomethionine-labelled protein crystals, indicating a doubled c unit-cell parameter. These reflections indicate small reorientations of the hexameric structural units, breaking the translational symmetry. TLS refinement of the selenomethionine-labelled protein structure at 1.55 A resolution revealed an anisotropic rigid-body libration of the hexameric units. The anisotropy is consistent with the static reorientation in the native protein crystals. These results are discussed as related to the crystal packing. The relation between the two structures suggests an analogy to structural changes during certain kinds of phase transitions that have been well studied in inorganic structural chemistry.

About this Structure

1U6J is a Single protein structure of sequence from Methanopyrus kandleri. Full crystallographic information is available from OCA.

Reference

The structure of F420-dependent methylenetetrahydromethanopterin dehydrogenase: a crystallographic 'superstructure' of the selenomethionine-labelled protein crystal structure., Warkentin E, Hagemeier CH, Shima S, Thauer RK, Ermler U, Acta Crystallogr D Biol Crystallogr. 2005 Feb;61(Pt 2):198-202. Epub 2005, Jan 19. PMID:15681872 Page seeded by OCA on Sat May 3 10:49:06 2008

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