5x3t
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==VapBC from Mycobacterium tuberculosis== | |
| - | + | <StructureSection load='5x3t' size='340' side='right' caption='[[5x3t]], [[Resolution|resolution]] 2.65Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5x3t]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5X3T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5X3T FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |
| - | [[Category: | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> |
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">vapB26, Rv0581 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU]), vapC26, Rv0582 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU])</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5x3t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5x3t OCA], [http://pdbe.org/5x3t PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5x3t RCSB], [http://www.ebi.ac.uk/pdbsum/5x3t PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5x3t ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/VPB26_MYCTU VPB26_MYCTU]] Antitoxin component of a type II toxin-antitoxin (TA) module. Upon expression in M.smegmatis neutralizes the effect of cognate toxin VapC26.<ref>PMID:20011113</ref> [[http://www.uniprot.org/uniprot/VPC26_MYCTU VPC26_MYCTU]] Toxic component of a type II toxin-antitoxin (TA) module. An RNase (By similarity). Upon expression in M.smegmatis inhibits colony formation. Its toxic effect is neutralized by coexpression with cognate antitoxin VapB26.[HAMAP-Rule:MF_00265]<ref>PMID:20011113</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Myctu]] | ||
| + | [[Category: Kang, S M]] | ||
| + | [[Category: Kim, D H]] | ||
| + | [[Category: Lee, B J]] | ||
| + | [[Category: Yoon, H J]] | ||
| + | [[Category: Antitoxin-toxin complex]] | ||
| + | [[Category: Ribonuclease]] | ||
| + | [[Category: Ta system]] | ||
Revision as of 11:04, 16 November 2017
VapBC from Mycobacterium tuberculosis
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