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Sandbox ggc6
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
| - | <scene name='75/752265/Transferase/8'>Overview of Transferase Structure</scene>. The CPK ligand forms direct and/or water-mediated hydrogen bonds with Glu506, Ser509, and Arg514. These three sites are shown and labeled within the structure. | + | <scene name='75/752265/Transferase/8'>Overview of Transferase Structure</scene>. The CPK ligand (22) forms direct and/or water-mediated hydrogen bonds with Glu506, Ser509, and Arg514. These three sites are shown and labeled within the structure. |
Color Key: | Color Key: | ||
Cyan-Alpha Helix; | Cyan-Alpha Helix; | ||
| Line 19: | Line 19: | ||
Dark Blue-Backbone/Main Chain; | Dark Blue-Backbone/Main Chain; | ||
Maroon-All Lys; | Maroon-All Lys; | ||
| - | Black-Ser509. | + | Black-Ser509; |
| + | Orange-Cys502. The N-free pyrazole of 22 interacts with Glu500 and Cys502 in the hinge region by two hydrogen bonds. | ||
Revision as of 16:56, 10 April 2017
Transferase/Transferase Inhibitor
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References
- ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
- ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644
