5nnc

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "5nnc" [edit=sysop:move=sysop])
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 5nnc is ON HOLD
+
==Crystal Structure of the first bromodomain of human BRD4 in complex with a diacetylated histone 4 peptide (H3K9ac/K14ac)==
-
 
+
<StructureSection load='5nnc' size='340' side='right' caption='[[5nnc]], [[Resolution|resolution]] 2.22&Aring;' scene=''>
-
Authors: Filippakopoulos, P., Picaud, S., Pike, A.C.W., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C.
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[5nnc]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NNC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5NNC FirstGlance]. <br>
-
Description: Crystal Structure of the first bromodomain of human BRD4 in complex with a diacetylated histone 4 peptide (H3K9ac/K14ac)
+
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ALY:N(6)-ACETYLLYSINE'>ALY</scene></td></tr>
-
[[Category: Unreleased Structures]]
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5nnc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nnc OCA], [http://pdbe.org/5nnc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5nnc RCSB], [http://www.ebi.ac.uk/pdbsum/5nnc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5nnc ProSAT]</span></td></tr>
-
[[Category: Pike, A.C.W]]
+
</table>
-
[[Category: Arrowsmith, C.H]]
+
== Disease ==
-
[[Category: Von Delft, F]]
+
[[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Note=A chromosomal aberration involving BRD4 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with NUT which produces a BRD4-NUT fusion protein.<ref>PMID:12543779</ref> <ref>PMID:11733348</ref>
 +
== Function ==
 +
[[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Plays a role in a process governing chromosomal dynamics during mitosis (By similarity).
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Arrowsmith, C H]]
 +
[[Category: Bountra, C]]
 +
[[Category: Delft, F von]]
 +
[[Category: Edwards, A M]]
 +
[[Category: Filippakopoulos, P]]
[[Category: Picaud, S]]
[[Category: Picaud, S]]
-
[[Category: Filippakopoulos, P]]
+
[[Category: Pike, A C.W]]
-
[[Category: Edwards, A.M]]
+
[[Category: Bromodomain]]
-
[[Category: Bountra, C]]
+
[[Category: Complex]]
 +
[[Category: Transcription]]

Revision as of 05:21, 16 May 2018

Crystal Structure of the first bromodomain of human BRD4 in complex with a diacetylated histone 4 peptide (H3K9ac/K14ac)

5nnc, resolution 2.22Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/5nnc"
Personal tools