5vc9

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'''Unreleased structure'''
 
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The entry 5vc9 is ON HOLD until Jun 28 2018
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==Zinc finger of human CXXC4 in complex with CpG DNA==
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<StructureSection load='5vc9' size='340' side='right' caption='[[5vc9]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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Authors: Liu, K., Xu, C., Tempel, W., Walker, J.R., Arrowsmith, C.H., Bountra, C., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5vc9]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VC9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5VC9 FirstGlance]. <br>
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Description: Zinc finger of human CXXC4 in complex with CpG DNA
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CXXC4, IDAX ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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[[Category: Arrowsmith, C.H]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5vc9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vc9 OCA], [http://pdbe.org/5vc9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5vc9 RCSB], [http://www.ebi.ac.uk/pdbsum/5vc9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5vc9 ProSAT]</span></td></tr>
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[[Category: Xu, C]]
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/CXXC4_HUMAN CXXC4_HUMAN]] Acts as a negative regulator of the Wnt signaling pathway via its interaction with DVL1.
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__TOC__
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</StructureSection>
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[[Category: Human]]
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[[Category: Arrowsmith, C H]]
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[[Category: Bountra, C]]
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[[Category: Edwards, A M]]
[[Category: Liu, K]]
[[Category: Liu, K]]
[[Category: Min, J]]
[[Category: Min, J]]
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[[Category: Edwards, A.M]]
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[[Category: Structural genomic]]
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[[Category: Walker, J.R]]
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[[Category: Structural Genomics Consortium (Sgc)]]
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[[Category: Bountra, C]]
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[[Category: Tempel, W]]
[[Category: Tempel, W]]
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[[Category: Walker, J R]]
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[[Category: Xu, C]]
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[[Category: Cxxc]]
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[[Category: Dna]]
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[[Category: Dna binding protein]]
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[[Category: Sgc]]

Revision as of 11:20, 6 November 2017

Zinc finger of human CXXC4 in complex with CpG DNA

5vc9, resolution 2.10Å

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