4l7c

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
==Structure of keap1 kelch domain with 2-{[(1S)-2-{[(1R,2S)-2-(1H-tetrazol-5-yl)cyclohexyl]carbonyl}-1,2,3,4-tetrahydroisoquinolin-1-yl]methyl}-1H-isoindole-1,3(2H)-dione==
==Structure of keap1 kelch domain with 2-{[(1S)-2-{[(1R,2S)-2-(1H-tetrazol-5-yl)cyclohexyl]carbonyl}-1,2,3,4-tetrahydroisoquinolin-1-yl]methyl}-1H-isoindole-1,3(2H)-dione==
-
<StructureSection load='4l7c' size='340' side='right' caption='[[4l7c]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
+
<StructureSection load='4l7c' size='340' side='right'caption='[[4l7c]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4l7c]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L7C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4L7C FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4l7c]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L7C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4L7C FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1VW:2-{[(1S)-2-{[(1R,2S)-2-(1H-TETRAZOL-5-YL)CYCLOHEXYL]CARBONYL}-1,2,3,4-TETRAHYDROISOQUINOLIN-1-YL]METHYL}-1H-ISOINDOLE-1,3(2H)-DIONE'>1VW</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1VW:2-{[(1S)-2-{[(1R,2S)-2-(1H-TETRAZOL-5-YL)CYCLOHEXYL]CARBONYL}-1,2,3,4-TETRAHYDROISOQUINOLIN-1-YL]METHYL}-1H-ISOINDOLE-1,3(2H)-DIONE'>1VW</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4l7d|4l7d]], [[4n1b|4n1b]]</td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4l7c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4l7c OCA], [https://pdbe.org/4l7c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4l7c RCSB], [https://www.ebi.ac.uk/pdbsum/4l7c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4l7c ProSAT]</span></td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">KEAP1, INRF2, KIAA0132, KLHL19 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4l7c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4l7c OCA], [http://pdbe.org/4l7c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4l7c RCSB], [http://www.ebi.ac.uk/pdbsum/4l7c PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4l7c ProSAT]</span></td></tr>
+
</table>
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/KEAP1_HUMAN KEAP1_HUMAN]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 20: Line 20:
==See Also==
==See Also==
-
*[[Kelch-like protein|Kelch-like protein]]
+
*[[Kelch-like protein 3D structures|Kelch-like protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Human]]
+
[[Category: Homo sapiens]]
-
[[Category: Albrecht, C]]
+
[[Category: Large Structures]]
-
[[Category: Barker, J J]]
+
[[Category: Albrecht C]]
-
[[Category: Barker, O]]
+
[[Category: Barker JJ]]
-
[[Category: Beaumont, E]]
+
[[Category: Barker O]]
-
[[Category: Bromidge, S]]
+
[[Category: Beaumont E]]
-
[[Category: Brookfield, F]]
+
[[Category: Bromidge S]]
-
[[Category: Brooks, M]]
+
[[Category: Brookfield F]]
-
[[Category: Ceska, T]]
+
[[Category: Brooks M]]
-
[[Category: Courade, J P]]
+
[[Category: Ceska T]]
-
[[Category: Crabbe, T]]
+
[[Category: Courade JP]]
-
[[Category: Duclos, S]]
+
[[Category: Crabbe T]]
-
[[Category: Fryatt, T]]
+
[[Category: Duclos S]]
-
[[Category: Jigorel, E]]
+
[[Category: Fryatt T]]
-
[[Category: Jnoff, E]]
+
[[Category: Jigorel E]]
-
[[Category: Kwong, J]]
+
[[Category: Jnoff E]]
-
[[Category: Sands, Z]]
+
[[Category: Kwong J]]
-
[[Category: Smith, M A]]
+
[[Category: Sands Z]]
-
[[Category: Beta-propeller]]
+
[[Category: Smith MA]]
-
[[Category: Kelch domain]]
+
-
[[Category: Kelch repeat motif]]
+
-
[[Category: Nrf2]]
+
-
[[Category: Protein-small molecule complex]]
+
-
[[Category: Stress sensor]]
+
-
[[Category: Transcription-inhibitor complex]]
+

Revision as of 09:36, 7 December 2022

Structure of keap1 kelch domain with 2-{[(1S)-2-{[(1R,2S)-2-(1H-tetrazol-5-yl)cyclohexyl]carbonyl}-1,2,3,4-tetrahydroisoquinolin-1-yl]methyl}-1H-isoindole-1,3(2H)-dione

PDB ID 4l7c

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4l7c"
Personal tools