Elongation factor
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | <StructureSection load=' | + | <StructureSection load='' size='350' side='right' caption='Structure of EF-Tu (cyan and magenta) with EF-Ts (green and yellow) (PDB entry [[1efu]])' scene='51/517376/Cv/1'> |
'''Elongation factors''' (EF) facilitate translational elongation during the formation of peptide bonds in the ribosome.<br /> | '''Elongation factors''' (EF) facilitate translational elongation during the formation of peptide bonds in the ribosome.<br /> | ||
| Line 132: | Line 132: | ||
**[[4v9o]], [[4v9p]] – EcEF in 30S ribosome <BR /> | **[[4v9o]], [[4v9p]] – EcEF in 30S ribosome <BR /> | ||
**[[4v9d]] – EcEF in 30S ribosome + antibiotics – Cryo-EM<BR /> | **[[4v9d]] – EcEF in 30S ribosome + antibiotics – Cryo-EM<BR /> | ||
| - | **[[2om7]], [[ | + | **[[2om7]], [[4v5f]] – TtEF in 70S ribosome – Cryo EM<BR /> |
**[[1zn0]], [[2rdo]], [[3j0e]], [[4v6t]], [[4v9b]] – EcEF in 30S ribosome – Cryo-EM<BR /> | **[[1zn0]], [[2rdo]], [[3j0e]], [[4v6t]], [[4v9b]] – EcEF in 30S ribosome – Cryo-EM<BR /> | ||
| Line 180: | Line 180: | ||
**[[1n0u]], [[2e1r]], [[2npf]] – yEF + antifungal drug<BR /> | **[[1n0u]], [[2e1r]], [[2npf]] – yEF + antifungal drug<BR /> | ||
**[[1zm2]], [[1zm3]], [[1zm4]], [[1zm9]], [[3b78]], [[3b82]], [[3b8h]], [[2zit]] – yEF + exotoxin<BR /> | **[[1zm2]], [[1zm3]], [[1zm4]], [[1zm9]], [[3b78]], [[3b82]], [[3b8h]], [[2zit]] – yEF + exotoxin<BR /> | ||
| - | **[[ | + | **[[4v4b]] - hEF in 40S ribosome – Cryo EM<BR /> |
**[[4cxg]], [[4cxh]] - rEF in 40S ribosome – Cryo EM<BR /> | **[[4cxg]], [[4cxh]] - rEF in 40S ribosome – Cryo EM<BR /> | ||
**[[2p8w]], [[2p8x]], [[3dny]] - yEF in 80S ribosome – Cryo EM<BR /> | **[[2p8w]], [[2p8x]], [[3dny]] - yEF in 80S ribosome – Cryo EM<BR /> | ||
| Line 238: | Line 238: | ||
**[[2c9w]], [[2izv]], [[2jz3]] – hEloBC + suppressor of cytokine signaling<br /> | **[[2c9w]], [[2izv]], [[2jz3]] – hEloBC + suppressor of cytokine signaling<br /> | ||
**[[3dcg]] – hEloBC + virion infectivity factor<br /> | **[[3dcg]] – hEloBC + virion infectivity factor<br /> | ||
| - | **[[ | + | **[[3zkj]] - hEloBC + ankyrin rep<br /> |
**[[1vcb]] – hEloBC + VHL<br /> | **[[1vcb]] – hEloBC + VHL<br /> | ||
**[[2fnj]] - mEloBC + GUSTAVUS | **[[2fnj]] - mEloBC + GUSTAVUS | ||
Revision as of 19:43, 28 December 2017
| |||||||||||
3D structures of elongation factor
Updated on 28-December-2017
References
- ↑ Takeshita D, Tomita K. Assembly of Q{beta} viral RNA polymerase with host translational elongation factors EF-Tu and -Ts. Proc Natl Acad Sci U S A. 2010 Sep 7;107(36):15733-8. Epub 2010 Aug 23. PMID:20798060 doi:http://dx.doi.org/10.1073/pnas.1006559107
- ↑ Jorgensen R, Merrill AR, Andersen GR. The life and death of translation elongation factor 2. Biochem Soc Trans. 2006 Feb;34(Pt 1):1-6. PMID:16246167 doi:http://dx.doi.org/10.1042/BST20060001
- ↑ Kawashima T, Berthet-Colominas C, Wulff M, Cusack S, Leberman R. The structure of the Escherichia coli EF-Tu.EF-Ts complex at 2.5 A resolution. Nature. 1996 Feb 8;379(6565):511-8. PMID:8596629 doi:http://dx.doi.org/10.1038/379511a0
