5nod
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==PASTA subunit 4 of Streptococcus pneumoniae STKP crystallized with PEG and succinate== | |
| - | + | <StructureSection load='5nod' size='340' side='right' caption='[[5nod]], [[Resolution|resolution]] 1.90Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5nod]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NOD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5NOD FirstGlance]. <br> | |
| - | + | </td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5nod FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nod OCA], [http://pdbe.org/5nod PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5nod RCSB], [http://www.ebi.ac.uk/pdbsum/5nod PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5nod ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/STKP_STRR6 STKP_STRR6]] Protein kinase involved in signal transduction pathways that regulate various cellular processes. Likely senses intracellular peptidoglycan subunits present in the cell division septa of actively growing cells; thus, intracellular unlinked peptidoglycan may serve as the signal molecules that trigger StkP phosphorylation activity on a set of substrates. Plays a crucial role in the regulation of cell shape and cell division of S.pneumoniae through control of at least DivIVA activity. Identified target substrates that are specifically phosphorylated by StkP in vivo, mainly on threonine residues, are DivIVA and StkP itself. Autophosphorylated StkP is a substrate for the cotranscribed protein phosphatase PhpP (shown in the avirulent strain Rx / Cp1015); PhpP and StkP appear to constitute a functional signaling couple in vivo.<ref>PMID:22211696</ref> <ref>PMID:22431591</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Non-specific serine/threonine protein kinase]] | ||
| + | [[Category: GALISSON, F]] | ||
| + | [[Category: GOUET, P]] | ||
| + | [[Category: GRANGEASSE, C]] | ||
| + | [[Category: GUEGUEN-CHAIGNON, V]] | ||
| + | [[Category: ZUCCHINI, L]] | ||
| + | [[Category: Extracellular domain]] | ||
| + | [[Category: Pasta]] | ||
| + | [[Category: Ser/thr kinase]] | ||
| + | [[Category: Streptococcus pneumoniae]] | ||
| + | [[Category: Transferase]] | ||
Revision as of 07:47, 8 November 2017
PASTA subunit 4 of Streptococcus pneumoniae STKP crystallized with PEG and succinate
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