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4wyg
From Proteopedia
(Difference between revisions)
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==Crystal structure of 7,8-diaminopelargonic acid synthase (BioA) from Mycobacterium tuberculosis complexed with a fragment hit== | ==Crystal structure of 7,8-diaminopelargonic acid synthase (BioA) from Mycobacterium tuberculosis complexed with a fragment hit== | ||
| - | <StructureSection load='4wyg' size='340' side='right' caption='[[4wyg]], [[Resolution|resolution]] 1.62Å' scene=''> | + | <StructureSection load='4wyg' size='340' side='right'caption='[[4wyg]], [[Resolution|resolution]] 1.62Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4wyg]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WYG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WYG FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[4wyg]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WYG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WYG FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3W1:1-{4-[(4-CHLORO-1H-PYRAZOL-1-YL)METHYL]PHENYL}METHANAMINE'>3W1</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3W1:1-{4-[(4-CHLORO-1H-PYRAZOL-1-YL)METHYL]PHENYL}METHANAMINE'>3W1</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4wya|4wya]], [[4wyc|4wyc]], [[4wyd|4wyd]], [[4wye|4wye]], [[4wyf|4wyf]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4wya|4wya]], [[4wyc|4wyc]], [[4wyd|4wyd]], [[4wye|4wye]], [[4wyf|4wyf]]</td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">bioA, Rv1568, MTCY336.35c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Adenosylmethionine--8-amino-7-oxononanoate_transaminase Adenosylmethionine--8-amino-7-oxononanoate transaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.1.62 2.6.1.62] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Adenosylmethionine--8-amino-7-oxononanoate_transaminase Adenosylmethionine--8-amino-7-oxononanoate transaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.1.62 2.6.1.62] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wyg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wyg OCA], [http://pdbe.org/4wyg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4wyg RCSB], [http://www.ebi.ac.uk/pdbsum/4wyg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4wyg ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wyg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wyg OCA], [http://pdbe.org/4wyg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4wyg RCSB], [http://www.ebi.ac.uk/pdbsum/4wyg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4wyg ProSAT]</span></td></tr> | ||
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</div> | </div> | ||
<div class="pdbe-citations 4wyg" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 4wyg" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Aminotransferase 3D structures|Aminotransferase 3D structures]] | ||
| + | *[[7%2C8-diaminopelargonic acid synthase 3D structures|7%2C8-diaminopelargonic acid synthase 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Adenosylmethionine--8-amino-7-oxononanoate transaminase]] | [[Category: Adenosylmethionine--8-amino-7-oxononanoate transaminase]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Myctu]] | ||
[[Category: Dai, R]] | [[Category: Dai, R]] | ||
[[Category: Finzel, B C]] | [[Category: Finzel, B C]] | ||
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[[Category: Plp]] | [[Category: Plp]] | ||
[[Category: Transaminase]] | [[Category: Transaminase]] | ||
| + | [[Category: Transferase-transferase inhibitor complex]] | ||
[[Category: Transferase/transferase inhibitor]] | [[Category: Transferase/transferase inhibitor]] | ||
Revision as of 08:22, 23 May 2019
Crystal structure of 7,8-diaminopelargonic acid synthase (BioA) from Mycobacterium tuberculosis complexed with a fragment hit
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