Enoyl-Acyl-Carrier Protein Reductase
From Proteopedia
(Difference between revisions)
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**[[4nqz]] - PaENR – ''Pseudomonas aeruginosa''<br /> | **[[4nqz]] - PaENR – ''Pseudomonas aeruginosa''<br /> | ||
**[[5cfz]] - EcENR – ''Escherichia coli''<br /> | **[[5cfz]] - EcENR – ''Escherichia coli''<br /> | ||
| - | **[[5gvj]] - | + | **[[5gvj]] - TmENR (mutant) – ''Thermotoga maritima''<br /> |
| + | **[[5ycv]], [[5ycx]] - BaENR (mutant) – ''Bacillus anthracis''<br /> | ||
*Enoyl-Acyl-Carrier Protein Reductase binary complex with NAD | *Enoyl-Acyl-Carrier Protein Reductase binary complex with NAD | ||
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**[[4m87]] - NmENR+NAD<br /> | **[[4m87]] - NmENR+NAD<br /> | ||
**[[5trt]] – BpENR + NAD<br /> | **[[5trt]] – BpENR + NAD<br /> | ||
| + | **[[5ycr]] - BaENR+NAD – ''Bacillus anthracis''<br /> | ||
*Other enoyl-Acyl-Carrier Protein Reductase binary complexes | *Other enoyl-Acyl-Carrier Protein Reductase binary complexes | ||
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**[[2pd3]] – HpENR+TCL – ''Helicobacter pylori''<br /> | **[[2pd3]] – HpENR+TCL – ''Helicobacter pylori''<br /> | ||
**[[2yw9]] – TtENR + NADP<br /> | **[[2yw9]] – TtENR + NADP<br /> | ||
| + | **[[5lb9]] – CtENR (mutant) + NADP<br /> | ||
**[[2fhs]] - EcENR+ acyl carrier protein <br /> | **[[2fhs]] - EcENR+ acyl carrier protein <br /> | ||
**[[2z6i]] – SpENR II + FMN – ''Streptococcus pneumoniae''<br /> | **[[2z6i]] – SpENR II + FMN – ''Streptococcus pneumoniae''<br /> | ||
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**[[4rlh]] – BpENR + inhibitor<br /> | **[[4rlh]] – BpENR + inhibitor<br /> | ||
**[[4w9n]] – ENR + TCL - human<br /> | **[[4w9n]] – ENR + TCL - human<br /> | ||
| + | **[[5gvh]] – TmENR + FMN <br /> | ||
*Enoyl-Acyl-Carrier Protein Reductase ternary complex | *Enoyl-Acyl-Carrier Protein Reductase ternary complex | ||
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**[[2wyw]] - TtENR+NAD+TCL<br /> | **[[2wyw]] - TtENR+NAD+TCL<br /> | ||
**[[2b36]], [[2b37]], [[4ohu]], [[4oim]], [[4oyr]] – MtENR+NAD+phenoxyphenol derivative<br /> | **[[2b36]], [[2b37]], [[4ohu]], [[4oim]], [[4oyr]] – MtENR+NAD+phenoxyphenol derivative<br /> | ||
| - | **[[2nsd]] – MtENR+NAD+piperidine derivative<br /> | + | **[[2nsd]], [[5oin]], [[5oip]] – MtENR+NAD+piperidine derivative<br /> |
**[[4u0j]], [[4tzt]], [[4tzk]], [[4trj]], [[4u0k]] - MtENR+NAD+pyrrolidine derivative<br /> | **[[4u0j]], [[4tzt]], [[4tzk]], [[4trj]], [[4u0k]] - MtENR+NAD+pyrrolidine derivative<br /> | ||
| + | **[[5oio]], [[5oif]], [[5oic]], [[5ois]], [[5oit]] – MtENR (mutant) +NAD+pyrazol derivative<br /> | ||
**[[4cod]], [[4bqp]], [[4bqr]], [[4bge]], [[4bii]], [[4oxk]], [[4oxn]], [[4oxy]], [[4r9r]], [[4r9s]], [[4d0r]], [[4d0s]], [[4qxm]], [[4tro]], [[4uvd]], [[4uve]], [[4uvg]], [[4uvh]], [[4uvi]], [[5g0s]], [[5g0t]], [[5g0u]], [[5g0v]], [[5g0w]], [[5jfo]], [[5mtp]], [[5mtq]], [[5mtr]], [[5ugs]], [[5ugt]], [[5ugu]] - MtENR+NAD + inhibitor<br /> | **[[4cod]], [[4bqp]], [[4bqr]], [[4bge]], [[4bii]], [[4oxk]], [[4oxn]], [[4oxy]], [[4r9r]], [[4r9s]], [[4d0r]], [[4d0s]], [[4qxm]], [[4tro]], [[4uvd]], [[4uve]], [[4uvg]], [[4uvh]], [[4uvi]], [[5g0s]], [[5g0t]], [[5g0u]], [[5g0v]], [[5g0w]], [[5jfo]], [[5mtp]], [[5mtq]], [[5mtr]], [[5ugs]], [[5ugt]], [[5ugu]] - MtENR+NAD + inhibitor<br /> | ||
| - | **[[4bgi]], [[5coq]], [[5cp8]], [[5cpb]], [[5cpf]] - MtENR (mutant) +NAD + inhibitor<br /> | + | **[[4bgi]], [[5coq]], [[5cp8]], [[5cpb]], [[5cpf]], [[5oil]], [[5oim]], [[5oiq]], [[5oir]] - MtENR (mutant) + NAD + inhibitor<br /> |
**[[1p44]] - MtENR+NAD+indole derivative<br /> | **[[1p44]] - MtENR+NAD+indole derivative<br /> | ||
**[[1bvr]] - MtENR+NAD+fatty-acyl substrate<br /> | **[[1bvr]] - MtENR+NAD+fatty-acyl substrate<br /> | ||
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**[[4alj]], [[4alk]], [[4bnf]], [[4bng]], [[4bnh]], [[4bni]], [[4bnj]], [[4bnk]], [[4bnl]], [[4bnm]], [[4bnn]], [[4d41]], [[4d42]], [[4d43]], [[4d45]] – SaENR (mutant) +NADP + phenoxyphenol derivative<br /> | **[[4alj]], [[4alk]], [[4bnf]], [[4bng]], [[4bnh]], [[4bni]], [[4bnj]], [[4bnk]], [[4bnl]], [[4bnm]], [[4bnn]], [[4d41]], [[4d42]], [[4d43]], [[4d45]] – SaENR (mutant) +NADP + phenoxyphenol derivative<br /> | ||
**[[4cv2]], [[4cv3]] – SaENR +NAD + inhibitor<br /> | **[[4cv2]], [[4cv3]] – SaENR +NAD + inhibitor<br /> | ||
| - | **[[4cuz]], [[4cv0]], [[4cv1]], [[4d44]], [[3nz9]] – SaENR (mutant) +NADP + inhibitor<br /> | + | **[[4cuz]], [[4cv0]], [[4cv1]], [[4d44]], [[3nz9]] – SaENR (mutant) + NADP + inhibitor<br /> |
**[[4nz9]] – SaENR +NADP + inhibitor<br /> | **[[4nz9]] – SaENR +NADP + inhibitor<br /> | ||
| - | **[[2qio]] - | + | **[[2qio]], [[5ycs]] - BaENR+NAD+TCL <br /> |
**[[2pd4]] – HpENR+NAD+diclosan<br /> | **[[2pd4]] – HpENR+NAD+diclosan<br /> | ||
**[[1mfp]], [[1i30]] - EcENR+NAD+indole derivative <br /> | **[[1mfp]], [[1i30]] - EcENR+NAD+indole derivative <br /> | ||
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**[[4nr0]] - PaENR+NAD+TCL <br /> | **[[4nr0]] - PaENR+NAD+TCL <br /> | ||
**[[4was]] – CtENR + NADPH + crotonyl CoA<br /> | **[[4was]] – CtENR + NADPH + crotonyl CoA<br /> | ||
| + | **[[5lbx]] – CtENR (mutant) + NADPH + crotonyl CoA<br /> | ||
}} | }} | ||
Revision as of 10:13, 13 May 2018
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3D Structures of Enoyl-Acyl-Carrier Protein Reductase
Updated on 13-May-2018
References
- ↑ Freundlich JS, Wang F, Vilcheze C, Gulten G, Langley R, Schiehser GA, Jacobus DP, Jacobs WR Jr, Sacchettini JC. Triclosan Derivatives: Towards Potent Inhibitors of Drug-Sensitive and Drug-Resistant Mycobacterium tuberculosis. ChemMedChem. 2009 Jan 7. PMID:19130456 doi:10.1002/cmdc.200800261
