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5vkc
From Proteopedia
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<StructureSection load='5vkc' size='340' side='right' caption='[[5vkc]], [[Resolution|resolution]] 2.31Å' scene=''> | <StructureSection load='5vkc' size='340' side='right' caption='[[5vkc]], [[Resolution|resolution]] 2.31Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5vkc]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VKC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5VKC FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[5vkc]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VKC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5VKC FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9EA:7-(3-{[4-(4-ACETYLPIPERAZIN-1-YL)PHENOXY]METHYL}-1,5-DIMETHYL-1H-PYRAZOL-4-YL)-3-{3-[(NAPHTHALEN-1-YL)OXY]PROPYL}-1-[(PYRIDIN-3-YL)METHYL]-1H-INDOLE-2-CARBOXYLIC+ACID'>9EA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9EA:7-(3-{[4-(4-ACETYLPIPERAZIN-1-YL)PHENOXY]METHYL}-1,5-DIMETHYL-1H-PYRAZOL-4-YL)-3-{3-[(NAPHTHALEN-1-YL)OXY]PROPYL}-1-[(PYRIDIN-3-YL)METHYL]-1H-INDOLE-2-CARBOXYLIC+ACID'>9EA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MCL1, BCL2L3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5vkc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vkc OCA], [http://pdbe.org/5vkc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5vkc RCSB], [http://www.ebi.ac.uk/pdbsum/5vkc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5vkc ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5vkc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vkc OCA], [http://pdbe.org/5vkc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5vkc RCSB], [http://www.ebi.ac.uk/pdbsum/5vkc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5vkc ProSAT]</span></td></tr> | ||
</table> | </table> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Human]] | ||
[[Category: Judge, R A]] | [[Category: Judge, R A]] | ||
[[Category: Souers, A J]] | [[Category: Souers, A J]] | ||
[[Category: Mcl-1]] | [[Category: Mcl-1]] | ||
[[Category: Signaling protein-inhibitor complex]] | [[Category: Signaling protein-inhibitor complex]] | ||
Revision as of 23:30, 15 November 2017
Crystal structure of MCL-1 in complex with a BIM competitive inhibitor
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