1v39

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[[Image:1v39.gif|left|200px]]
[[Image:1v39.gif|left|200px]]
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{{Structure
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<!--
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|PDB= 1v39 |SIZE=350|CAPTION= <scene name='initialview01'>1v39</scene>, resolution 1.8&Aring;
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The line below this paragraph, containing "STRUCTURE_1v39", creates the "Structure Box" on the page.
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|SITE=
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=M7G:7N-METHYL-8-HYDROGUANOSINE-5&#39;-DIPHOSPHATE'>M7G</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Polynucleotide_adenylyltransferase Polynucleotide adenylyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.19 2.7.7.19] </span>
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or leave the SCENE parameter empty for the default display.
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|GENE=
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-->
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|DOMAIN=
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{{STRUCTURE_1v39| PDB=1v39 | SCENE= }}
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1v39 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v39 OCA], [http://www.ebi.ac.uk/pdbsum/1v39 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1v39 RCSB]</span>
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}}
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'''DC26 MUTANT OF VACCINIA VIRUS PROTEIN VP39 IN COMPLEX WITH S-ADENOSYLHOMOCYSTEINE AND M7G(5')PPPG'''
'''DC26 MUTANT OF VACCINIA VIRUS PROTEIN VP39 IN COMPLEX WITH S-ADENOSYLHOMOCYSTEINE AND M7G(5')PPPG'''
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[[Category: Hodel, A E.]]
[[Category: Hodel, A E.]]
[[Category: Quiocho, F A.]]
[[Category: Quiocho, F A.]]
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[[Category: methyltransferase]]
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[[Category: Methyltransferase]]
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[[Category: mrna processing]]
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[[Category: Mrna processing]]
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[[Category: poly(a) polymerase]]
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[[Category: Rna cap]]
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[[Category: rna cap]]
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[[Category: Transcription]]
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[[Category: transcription]]
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[[Category: Vaccinia]]
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[[Category: vaccinia]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 12:01:29 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 00:18:54 2008''
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Revision as of 09:01, 3 May 2008

Image:1v39.gif

Template:STRUCTURE 1v39

DC26 MUTANT OF VACCINIA VIRUS PROTEIN VP39 IN COMPLEX WITH S-ADENOSYLHOMOCYSTEINE AND M7G(5')PPPG


Overview

The specific binding of N7-methylguanine cap analogues to the RNA methyltransferase VP39 was observed through X-ray crystallography, providing a prototypical structure for a complex between a protein and an mRNA 5' cap.

About this Structure

1V39 is a Single protein structure of sequence from Vaccinia virus. Full crystallographic information is available from OCA.

Reference

Specific protein recognition of an mRNA cap through its alkylated base., Hodel AE, Gershon PD, Shi X, Wang SM, Quiocho FA, Nat Struct Biol. 1997 May;4(5):350-4. PMID:9145102 Page seeded by OCA on Sat May 3 12:01:29 2008

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OCA

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