Exportin

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**[[3gb8]] – hXPO + RNA U transporter 1 <br />
**[[3gb8]] – hXPO + RNA U transporter 1 <br />
-
**[[3gjx]] – hXPO + RNA U transporter 1 + GTP-binding nuclear protein RAN<br />
+
**[[3gjx]] – hXPO + RNA U transporter 1 + RAN<br />
-
**[[5dis]] – hXPO + GTP-binding nuclear protein RAN + RNA U transporter 1 + MBP<br />
+
**[[5dis]] – hXPO + RAN + RNA U transporter 1 + MBP<br />
-
**[[3m1i]], [[4gpt]], [[4gmx]], [[4hat]], [[4hb2]], [[5jlj]] – yXPO (mutant) + GTP-binding nuclear protein RAN + RAN-specific GTPase-activating protein <br />
+
**[[3m1i]], [[4gpt]], [[4gmx]], [[4hat]], [[4hb2]], [[5jlj]] – yXPO (mutant) + RAN + RANBP1 <br />
-
**[[3wyf]] – yXPO + GTP-binding nuclear protein RAN + RAN-specific GTPase-activating protein <br />
+
**[[3wyf]] – yXPO + RAN + RANBP1 <br />
-
**[[3wyg]] – yXPO + GTP-binding nuclear protein RAN + PKI-alpha<br />
+
**[[3wyg]] – yXPO + RAN + PKI-α<br />
-
**[[4hau]], [[4hav]], [[4haw]], [[4hax]], [[4hay]], [[4haz]], [[4hb0]], [[4hb3]], [[4hb4]] – yXPO (mutant) + GTP-binding nuclear protein RAN + RAN-specific GTPase-activating protein + antibiotic<br />
+
**[[4hau]], [[4hav]], [[4haw]], [[4hax]], [[4hay]], [[4haz]], [[4hb0]], [[4hb3]], [[4hb4]] – yXPO (mutant) + RAN + RANBP1 + antibiotic<br />
-
**[[5dh9]], [[5dha]], [[5dhf]], [[5di9]], [[5uwj]] - yXPO (mutant) + GTP-binding nuclear protein RAN + RAN-specific GTPase-activating protein + signal peptide<br />
+
**[[5dh9]], [[5dha]], [[5dhf]], [[5di9]], [[5uwj]], [[5dif]] - yXPO (mutant) + RAN + RANBP1 + signal peptide<br />
-
**[[5uwo]], [[5uwp]], [[5uwq]], [[5uwr]], [[5uws]], [[5uwt]], [[5uwu]], [[5uww]], [[5uwi]], [[5uwh]] - yXPO + GTP-binding nuclear protein RAN + RAN-specific GTPase-activating protein + signal peptide<br />
+
**[[5uwo]], [[5uwp]], [[5uwq]], [[5uwr]], [[5uws]], [[5uwt]], [[5uwu]], [[5uww]], [[5uwi]], [[5uwh]] - yXPO + RAN + RANBP1 + signal peptide<br />
-
**[[3nby]], [[3nbz]], [[3nc0]] – mXPO + RNA U transporter 1 + RAN-specific GTPase-activating protein - mouse<br />
+
**[[5xoj]] - yXPO (mutant) + GSP1P + PKI-a + NUP42 peptide + GTP<br />
-
**[[3nc1]] – mXPO + RAN-specific GTPase-activating protein<br />
+
**[[3nby]], [[3nbz]], [[3nc0]] – mXPO + RNA U transporter 1 + RANBP1 - mouse<br />
-
**[[2l1l]] – hXPO residues 504-630 + cAMP-dependent protein kinase inhibitor α - NMR<br />
+
**[[3nc1]] – mXPO + RANBP1<br />
 +
**[[2l1l]] – hXPO residues 504-630 + PKI-α - NMR<br />
*XPO-t
*XPO-t
**[[3ibv]] – fyXPO – fission yeast<br />
**[[3ibv]] – fyXPO – fission yeast<br />
-
**[[3icq]] – fyXPO + GTP-binding nuclear protein + RNA <br />
+
**[[3icq]] – fyXPO + RAN homolog + RNA <br />
*XPO-4
*XPO-4
-
**[[5dlq]] – mXPO (mutant) + GTP-binding nuclear protein RAN + EIF5A1<br />
+
**[[5dlq]] – mXPO (mutant) + RAN + EIF5A1<br />
*XPO-5
*XPO-5

Revision as of 08:51, 22 May 2018

Structure of yeast exportin-5 (magenta) complex with GTPaseRan (cyan), Mg+2 (green) and RNA (PDB code 3icq).

Drag the structure with the mouse to rotate

3D structures of exportin

Updated on 22-May-2018

References

  1. ↑ Kohler A, Hurt E. Exporting RNA from the nucleus to the cytoplasm. Nat Rev Mol Cell Biol. 2007 Oct;8(10):761-73. PMID:17786152 doi:http://dx.doi.org/10.1038/nrm2255
  2. ↑ Cook AG, Fukuhara N, Jinek M, Conti E. Structures of the tRNA export factor in the nuclear and cytosolic states. Nature. 2009 Sep 3;461(7260):60-5. PMID:19680239 doi:10.1038/nature08394

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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