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5v7w
From Proteopedia
(Difference between revisions)
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<StructureSection load='5v7w' size='340' side='right' caption='[[5v7w]], [[Resolution|resolution]] 2.65Å' scene=''> | <StructureSection load='5v7w' size='340' side='right' caption='[[5v7w]], [[Resolution|resolution]] 2.65Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5v7w]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5V7W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5V7W FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[5v7w]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5V7W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5V7W FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=91J:2-{[(1-METHYLPIPERIDIN-4-YL)METHYL]AMINO}-5,6,7,8-TETRAHYDRO[1]BENZOTHIENO[2,3-D]PYRIMIDIN-4(3H)-ONE'>91J</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=91J:2-{[(1-METHYLPIPERIDIN-4-YL)METHYL]AMINO}-5,6,7,8-TETRAHYDRO[1]BENZOTHIENO[2,3-D]PYRIMIDIN-4(3H)-ONE'>91J</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5v7t|5v7t]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5v7t|5v7t]]</td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PARP14, BAL2, KIAA1268 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/NAD(+)_ADP-ribosyltransferase NAD(+) ADP-ribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.30 2.4.2.30] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/NAD(+)_ADP-ribosyltransferase NAD(+) ADP-ribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.30 2.4.2.30] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5v7w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5v7w OCA], [http://pdbe.org/5v7w PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5v7w RCSB], [http://www.ebi.ac.uk/pdbsum/5v7w PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5v7w ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5v7w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5v7w OCA], [http://pdbe.org/5v7w PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5v7w RCSB], [http://www.ebi.ac.uk/pdbsum/5v7w PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5v7w ProSAT]</span></td></tr> | ||
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</div> | </div> | ||
<div class="pdbe-citations 5v7w" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 5v7w" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Poly (ADP-ribose) polymerase|Poly (ADP-ribose) polymerase]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Human]] | ||
[[Category: Hirozane, M]] | [[Category: Hirozane, M]] | ||
[[Category: Saikatendu, k s]] | [[Category: Saikatendu, k s]] | ||
[[Category: Human parp14]] | [[Category: Human parp14]] | ||
[[Category: Transferase-transferase inhibitor complex]] | [[Category: Transferase-transferase inhibitor complex]] | ||
Current revision
Crystal structure of human PARP14 bound to 2-{[(1-methylpiperidin-4-yl)methyl]amino}-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one inhibitor
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