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5jr5
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5jr5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jr5 OCA], [http://pdbe.org/5jr5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jr5 RCSB], [http://www.ebi.ac.uk/pdbsum/5jr5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5jr5 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5jr5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jr5 OCA], [http://pdbe.org/5jr5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jr5 RCSB], [http://www.ebi.ac.uk/pdbsum/5jr5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5jr5 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Elemental sulfur exists primarily as an S80 ring and serves as terminal electron acceptor for a variety of sulfur-fermenting bacteria. Hyperthermophilic archaea from black smoker vents are an exciting research tool to advance our knowledge of sulfur respiration under extreme conditions. Here, we use a hybrid method approach to demonstrate that the proteinaceous cavities of the S-layer nanotube of the hyperthermophilic archaeon Staphylothermus marinus act as a storage reservoir for cyclo-octasulfur S8. Fully atomistic molecular dynamics (MD) simulations were performed and the method of multiconfigurational thermodynamic integration was employed to compute the absolute free energy for transferring a ring of elemental sulfur S8 from an aqueous bath into the largest hydrophobic cavity of a fragment of archaeal tetrabrachion. Comparisons with earlier MD studies of the free energy of hydration as a function of water occupancy in the same cavity of archaeal tetrabrachion show that the sulfur ring is energetically favored over water. | ||
| + | |||
| + | Archaea S-layer nanotube from a "black smoker" in complex with cyclo-octasulfur (S8 ) rings.,McDougall M, Francisco O, Harder-Viddal C, Roshko R, Meier M, Stetefeld J Proteins. 2017 Sep 14. doi: 10.1002/prot.25385. PMID:28905430<ref>PMID:28905430</ref> | ||
| + | |||
| + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| + | </div> | ||
| + | <div class="pdbe-citations 5jr5" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Revision as of 07:05, 25 October 2017
RHCC in Complex with Elemental Sulfur
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Categories: McDougall, M | Meier, M | Stetefeld, J | Archaea | Coiled-coil | Nanotube | Protein binding | Sulfur
