5nxd

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m (Protected "5nxd" [edit=sysop:move=sysop])
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'''Unreleased structure'''
 
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The entry 5nxd is ON HOLD
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==LIM Domain Kinase 2 (LIMK2) In Complex With TH-300==
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<StructureSection load='5nxd' size='340' side='right' caption='[[5nxd]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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Authors: Mathea, S., Salah, E., Hanke, T., Newman, J.A., Oerum, S., Wang, D., Burgess-Brown, N., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Bullock, A.N., Knapp, S.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5nxd]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NXD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5NXD FirstGlance]. <br>
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Description: LIM Domain Kinase 2 (LIMK2)In Complex With TH-300
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9D8:4-[(3-CHLOROPHENYL)SULFAMOYL]-~{N}-(PHENYLMETHYL)-~{N}-PROPYL-BENZAMIDE'>9D8</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
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[[Category: Oerum, S]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5nxd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nxd OCA], [http://pdbe.org/5nxd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5nxd RCSB], [http://www.ebi.ac.uk/pdbsum/5nxd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5nxd ProSAT]</span></td></tr>
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[[Category: Mathea, S]]
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</table>
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[[Category: Arrowsmith, C.H]]
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== Function ==
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[[http://www.uniprot.org/uniprot/LIMK2_HUMAN LIMK2_HUMAN]] Displays serine/threonine-specific phosphorylation of myelin basic protein and histone (MBP) in vitro.<ref>PMID:10436159</ref> <ref>PMID:11018042</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: Arrowsmith, C H]]
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[[Category: Bountra, C]]
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[[Category: Bullock, A N]]
[[Category: Burgess-Brown, N]]
[[Category: Burgess-Brown, N]]
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[[Category: Wang, D]]
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[[Category: Delft, F von]]
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[[Category: Von Delft, F]]
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[[Category: Edwards, A M]]
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[[Category: Bullock, A.N]]
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[[Category: Hanke, T]]
[[Category: Knapp, S]]
[[Category: Knapp, S]]
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[[Category: Hanke, T]]
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[[Category: Mathea, S]]
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[[Category: Edwards, A.M]]
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[[Category: Newman, J A]]
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[[Category: Newman, J.A]]
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[[Category: Oerum, S]]
[[Category: Salah, E]]
[[Category: Salah, E]]
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[[Category: Bountra, C]]
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[[Category: Wang, D]]
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[[Category: Kinase actin cytoskeleton inhibitor dfg-out]]
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[[Category: Transferase]]

Revision as of 13:47, 24 May 2017

LIM Domain Kinase 2 (LIMK2) In Complex With TH-300

5nxd, resolution 1.90Å

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