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5mjb

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==Kinase domain of human EphB1, G703C mutant, covalently bound to a quinazoline-based inhibitor==
==Kinase domain of human EphB1, G703C mutant, covalently bound to a quinazoline-based inhibitor==
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<StructureSection load='5mjb' size='340' side='right' caption='[[5mjb]], [[Resolution|resolution]] 2.23&Aring;' scene=''>
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<StructureSection load='5mjb' size='340' side='right'caption='[[5mjb]], [[Resolution|resolution]] 2.23&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5mjb]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MJB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5MJB FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5mjb]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MJB OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5MJB FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=7O3:2-CHLORANYL-~{N}-[4-[(2-CHLORANYL-5-OXIDANYL-PHENYL)AMINO]QUINAZOLIN-7-YL]ETHANAMIDE'>7O3</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7O3:2-CHLORANYL-~{N}-[4-[(2-CHLORANYL-5-OXIDANYL-PHENYL)AMINO]QUINAZOLIN-7-YL]ETHANAMIDE'>7O3</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PTR:O-PHOSPHOTYROSINE'>PTR</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PTR:O-PHOSPHOTYROSINE'>PTR</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5mjb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mjb OCA], [http://pdbe.org/5mjb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5mjb RCSB], [http://www.ebi.ac.uk/pdbsum/5mjb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5mjb ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5mjb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mjb OCA], [http://pdbe.org/5mjb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5mjb RCSB], [http://www.ebi.ac.uk/pdbsum/5mjb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5mjb ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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</div>
</div>
<div class="pdbe-citations 5mjb" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5mjb" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Ephrin receptor 3D structures|Ephrin receptor 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Chen, Y C]]
[[Category: Chen, Y C]]

Revision as of 07:20, 19 August 2020

Kinase domain of human EphB1, G703C mutant, covalently bound to a quinazoline-based inhibitor

PDB ID 5mjb

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