Focal adhesion kinase
From Proteopedia
(Difference between revisions)
| Line 45: | Line 45: | ||
**[[2j0j]], [[2j0k]], [[2j0m]] - cFAK1 kinase + FERM domains<br /> | **[[2j0j]], [[2j0k]], [[2j0m]] - cFAK1 kinase + FERM domains<br /> | ||
| - | **[[2aeh]], [[2al6]] - | + | **[[2aeh]], [[2al6]] - cFAK1<br /> |
| - | **[[3zdt]] - | + | **[[3zdt]] - cFAK1 (mutant)<br /> |
**[[4cye]] - hFAK1<br /> | **[[4cye]] - hFAK1<br /> | ||
| - | **[[4ny0]] - | + | **[[4ny0]] - hFAK1 (mutant)<br /> |
| + | |||
| + | *''FAK1 FAT domain'' | ||
| + | |||
| + | **[[6bz3]] – mFAK1 + netrin receptor peptide<br /> | ||
*Focal adhesion kinase 2 (FAK2) See Pyk2 in [[Tyrosine kinase]] | *Focal adhesion kinase 2 (FAK2) See Pyk2 in [[Tyrosine kinase]] | ||
Revision as of 07:52, 28 May 2018
| |||||||||||
3D Structures of focal adhesion kinase
Updated on 28-May-2018
References
- ↑ Mitra SK, Hanson DA, Schlaepfer DD. Focal adhesion kinase: in command and control of cell motility. Nat Rev Mol Cell Biol. 2005 Jan;6(1):56-68. PMID:15688067 doi:http://dx.doi.org/10.1038/nrm1549
- ↑ Cabrita MA, Jones LM, Quizi JL, Sabourin LA, McKay BC, Addison CL. Focal adhesion kinase inhibitors are potent anti-angiogenic agents. Mol Oncol. 2011 Dec;5(6):517-26. doi: 10.1016/j.molonc.2011.10.004. Epub 2011 Oct, 20. PMID:22075057 doi:http://dx.doi.org/10.1016/j.molonc.2011.10.004
- ↑ Lietha D, Eck MJ. Crystal structures of the FAK kinase in complex with TAE226 and related bis-anilino pyrimidine inhibitors reveal a helical DFG conformation. PLoS ONE. 2008;3(11):e3800. Epub 2008 Nov 24. PMID:19030106 doi:10.1371/journal.pone.0003800
