5nz0
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Structure of Transcriptional Regulatory Repressor Protein - EthR from Mycobacterium Tuberculosis in complex with linezolid== | |
| - | + | <StructureSection load='5nz0' size='340' side='right' caption='[[5nz0]], [[Resolution|resolution]] 1.82Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5nz0]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NZ0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5NZ0 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=ZLD:N-{[(5S)-3-(3-FLUORO-4-MORPHOLIN-4-YLPHENYL)-2-OXO-1,3-OXAZOLIDIN-5-YL]METHYL}ACETAMIDE'>ZLD</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5nz0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nz0 OCA], [http://pdbe.org/5nz0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5nz0 RCSB], [http://www.ebi.ac.uk/pdbsum/5nz0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5nz0 ProSAT]</span></td></tr> |
| - | [[Category: Blundell, T | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/ETHR_MYCTU ETHR_MYCTU]] Involved in the repression of the monooxygenase EthA which is responsible of the formation of the active metabolite of ethionamide (ETH).<ref>PMID:10869356</ref> <ref>PMID:10944230</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Blaszczyk, M]] | ||
| + | [[Category: Blundell, T L]] | ||
[[Category: Mendes, V]] | [[Category: Mendes, V]] | ||
| - | [[Category: | + | [[Category: Nikiforov, P O]] |
| - | [[Category: | + | [[Category: Boosting effect]] |
| + | [[Category: Ethr]] | ||
| + | [[Category: Represor]] | ||
| + | [[Category: Transcription]] | ||
Revision as of 05:26, 30 May 2018
Structure of Transcriptional Regulatory Repressor Protein - EthR from Mycobacterium Tuberculosis in complex with linezolid
| |||||||||||
