5nz1
From Proteopedia
(Difference between revisions)
m (Protected "5nz1" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Structure of Transcriptional Regulatory Repressor Protein - EthR from Mycobacterium Tuberculosis in complex with sutezolid== | |
| - | + | <StructureSection load='5nz1' size='340' side='right' caption='[[5nz1]], [[Resolution|resolution]] 2.33Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5nz1]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NZ1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5NZ1 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9EN:~{N}-[[(5~{S})-3-(3-fluoranyl-4-thiomorpholin-4-yl-phenyl)-2-oxidanylidene-1,3-oxazolidin-5-yl]methyl]ethanamide'>9EN</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5nz1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nz1 OCA], [http://pdbe.org/5nz1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5nz1 RCSB], [http://www.ebi.ac.uk/pdbsum/5nz1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5nz1 ProSAT]</span></td></tr> |
| - | [[Category: Blundell, T | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/ETHR_MYCTU ETHR_MYCTU]] Involved in the repression of the monooxygenase EthA which is responsible of the formation of the active metabolite of ethionamide (ETH).<ref>PMID:10869356</ref> <ref>PMID:10944230</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Blaszczyk, M]] | ||
| + | [[Category: Blundell, T L]] | ||
[[Category: Mendes, V]] | [[Category: Mendes, V]] | ||
| - | [[Category: | + | [[Category: Nikiforov, P O]] |
| - | [[Category: | + | [[Category: Boosting effect]] |
| + | [[Category: Ethr]] | ||
| + | [[Category: Represor]] | ||
| + | [[Category: Transcription]] | ||
Revision as of 05:26, 30 May 2018
Structure of Transcriptional Regulatory Repressor Protein - EthR from Mycobacterium Tuberculosis in complex with sutezolid
| |||||||||||
