5vt1
From Proteopedia
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| - | ==Crystal Structure of the Human CAMKK2B bound to a benzamide inhibitor== | + | ==Crystal Structure of the Human CAMKK2B bound to a thiadiazinone benzamide inhibitor== |
<StructureSection load='5vt1' size='340' side='right' caption='[[5vt1]], [[Resolution|resolution]] 1.90Å' scene=''> | <StructureSection load='5vt1' size='340' side='right' caption='[[5vt1]], [[Resolution|resolution]] 1.90Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5vt1]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VT1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5VT1 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[5vt1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VT1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5VT1 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9JS:4-({5-[(3-HYDROXY-4-METHYLPHENYL)AMINO]-4-OXO-4H-1,2,6-THIADIAZIN-3-YL}AMINO)BENZAMIDE'>9JS</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9JS:4-({5-[(3-HYDROXY-4-METHYLPHENYL)AMINO]-4-OXO-4H-1,2,6-THIADIAZIN-3-YL}AMINO)BENZAMIDE'>9JS</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CAMKK2, CAMKKB, KIAA0787 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Calcium/calmodulin-dependent_protein_kinase Calcium/calmodulin-dependent protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.17 2.7.11.17] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Calcium/calmodulin-dependent_protein_kinase Calcium/calmodulin-dependent protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.17 2.7.11.17] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5vt1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vt1 OCA], [http://pdbe.org/5vt1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5vt1 RCSB], [http://www.ebi.ac.uk/pdbsum/5vt1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5vt1 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5vt1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vt1 OCA], [http://pdbe.org/5vt1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5vt1 RCSB], [http://www.ebi.ac.uk/pdbsum/5vt1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5vt1 ProSAT]</span></td></tr> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Calcium/calmodulin-dependent protein kinase]] | [[Category: Calcium/calmodulin-dependent protein kinase]] | ||
| - | [[Category: | + | [[Category: Human]] |
[[Category: Arruda, P]] | [[Category: Arruda, P]] | ||
| + | [[Category: Asquith, C R.M]] | ||
[[Category: Counago, R M]] | [[Category: Counago, R M]] | ||
[[Category: Edwards, A M]] | [[Category: Edwards, A M]] | ||
[[Category: Gileadi, O]] | [[Category: Gileadi, O]] | ||
| + | [[Category: Kalogirou, A S]] | ||
| + | [[Category: Koutentis, P A]] | ||
[[Category: Structural genomic]] | [[Category: Structural genomic]] | ||
[[Category: Protein kinase domain]] | [[Category: Protein kinase domain]] | ||
Revision as of 07:39, 29 November 2017
Crystal Structure of the Human CAMKK2B bound to a thiadiazinone benzamide inhibitor
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