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Gp41

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<StructureSection load='1aik' size='340' side='right' caption='Gp41 N chain (magenta) and C chain (pink) with acetylated ends, [[1aik]].' scene=''>
<StructureSection load='1aik' size='340' side='right' caption='Gp41 N chain (magenta) and C chain (pink) with acetylated ends, [[1aik]].' scene=''>
== Function ==
== Function ==
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**[[1df4]], [[1df5]], [[1qr8]], [[1qr9]], [[1dlb]], [[1jpx]] – Gp41 core<br />
**[[1df4]], [[1df5]], [[1qr8]], [[1qr9]], [[1dlb]], [[1jpx]] – Gp41 core<br />
**[[1f23]], [[1k33]], [[1k34]], [[1i5x]], [[1i5y]], [[2ot5]] – Gp41 core (mutant)<br />
**[[1f23]], [[1k33]], [[1k34]], [[1i5x]], [[1i5y]], [[2ot5]] – Gp41 core (mutant)<br />
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**[[2z2t]], [[2zzo]], [[3aha]], [[3vie]], [[2r3c]], [[2r5b]], [[2r5d]], [[3l36]], [[3l37]], [[3vgy]], [[3vh7]], [[3vtp]], [[3vu5]], [[3vu6]] – Gp41 N-heptad repeat + Gp41 fusion inhibitor peptide<br />
+
**[[5ka6]], [[5ka5]] – Gp41 transmembrane (mutant)<br />
 +
**[[2z2t]], [[2zzo]], [[3aha]], [[3vie]], [[2r3c]], [[2r5b]], [[2r5d]], [[3l36]], [[3l37]], [[3vgy]], [[3vh7]], [[3vtp]], [[3vu5]], [[3vu6]], [[5h0n]] – Gp41 N-heptad repeat + Gp41 fusion inhibitor peptide<br />
**[[2zfc]] – Gp41 N-peptide <br />
**[[2zfc]] – Gp41 N-peptide <br />
**[[4i2l]] – Gp41 N-peptide (mutant)<br />
**[[4i2l]] – Gp41 N-peptide (mutant)<br />
**[[3u91]] – Gp41 N-terminal <br />
**[[3u91]] – Gp41 N-terminal <br />
**[[4hlr]] – Gp41 N-terminal (mutant) <br />
**[[4hlr]] – Gp41 N-terminal (mutant) <br />
 +
**[[5v8l]], [[5v8m]], [[5uty]], [[5utf]], [[5um8]], [[5jsa]], [[5js9]], [[5i8h]], [[5d9q]], [[5cjx]], [[5c7k]] – Gp41 + Gp120 + antibody<br />
 +
**[[5u1f]], [[5thr]] – Gp41 + Gp120 + antibody + CD4<br />
 +
**[[5fyk]], [[5fyj]], [[4nco]] – Gp41 + Gp120 (mutant) + antibody<br />
 +
**[[5hm1]] – Gp41 + llama antibody <br />
**[[3o3x]] – arGp41 - artificial<br />
**[[3o3x]] – arGp41 - artificial<br />
**[[4dzu]] – arGp41 + 3-α<br />
**[[4dzu]] – arGp41 + 3-α<br />

Revision as of 09:50, 4 June 2017

Gp41 N chain (magenta) and C chain (pink) with acetylated ends, 1aik.

Drag the structure with the mouse to rotate

3D Structures of Gp41

Updated on 04-June-2017

References

  1. ↑ Chan DC, Kim PS. HIV entry and its inhibition. Cell. 1998 May 29;93(5):681-4. PMID:9630213
  2. ↑ Root MJ, Steger HK. HIV-1 gp41 as a target for viral entry inhibition. Curr Pharm Des. 2004;10(15):1805-25. PMID:15180542

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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