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Sandbox 7784

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Current revision (19:12, 18 June 2017) (edit) (undo)
 
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Tacrine was the first cholinesterase inhibitor approved for the treatment of Alzheimer's disease.
Tacrine was the first cholinesterase inhibitor approved for the treatment of Alzheimer's disease.
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Tacrine’s ringed structure is stacked between the <scene name='76/761691/Tacrine/2'>aromatic rings of Trp84 and Phe330</scene>.<ref>PMID:415649</ref>
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Tacrine’s ringed structure is stacked between the <scene name='76/761691/Tacrine/2'>aromatic rings of Trp84 and Phe330</scene><ref>PMID:8415649</ref>.
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*Harel et al Silman & Sussman (1993) "Quaternary ligand binding to aromatic residues in the active-site gorge of acetylcholinesterase" PNAS, 90, 9031-5.
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</StructureSection>
</StructureSection>
==References==
==References==
<references/>
<references/>

Current revision

Your Heading Here (maybe something like 'Structure')

Escherichia coli reca protein-bound DNA (PDB entry 1acj)

Drag the structure with the mouse to rotate

References

  1. ↑ Harel M, Schalk I, Ehret-Sabatier L, Bouet F, Goeldner M, Hirth C, Axelsen PH, Silman I, Sussman JL. Quaternary ligand binding to aromatic residues in the active-site gorge of acetylcholinesterase. Proc Natl Acad Sci U S A. 1993 Oct 1;90(19):9031-5. PMID:8415649
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