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(New page: ==Your Heading Here (maybe something like 'Structure')== <StructureSection load='3rec' size='350' side='right' caption='Escherichia coli reca protein-bound DNA (PDB entry 3rec)' scene=...)
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Tacrine was the first cholinesterase inhibitor approved for the treatment of Alzheimer's disease.
Tacrine was the first cholinesterase inhibitor approved for the treatment of Alzheimer's disease.
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Tacrine’s ringed structure is stacked between the aromatic rings of Trp84 and Phe330.
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Tacrine’s ringed structure is stacked between the aromatic rings of Trp84 and Phe330.<ref>PMID:8415649</ref>
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*Harel et al Silman & Sussman (1993) "Quaternary ligand binding to aromatic residues in the active-site gorge of acetylcholinesterase" PNAS, 90, 9031-5.
 
</StructureSection>
</StructureSection>
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== References ==
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<references/>

Revision as of 06:07, 19 June 2017

Your Heading Here (maybe something like 'Structure')

Escherichia coli reca protein-bound DNA (PDB entry 3rec)

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References

  1. Harel M, Schalk I, Ehret-Sabatier L, Bouet F, Goeldner M, Hirth C, Axelsen PH, Silman I, Sussman JL. Quaternary ligand binding to aromatic residues in the active-site gorge of acetylcholinesterase. Proc Natl Acad Sci U S A. 1993 Oct 1;90(19):9031-5. PMID:8415649
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