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Integrin

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Line 75: Line 75:
**[[1dzi]], [[4bj3]] - hIG I domain + collagen peptide<br />
**[[1dzi]], [[4bj3]] - hIG I domain + collagen peptide<br />
**[[1v7p]] - hIG I domain (mutant) + EMS16 + Mn<br />
**[[1v7p]] - hIG I domain (mutant) + EMS16 + Mn<br />
 +
**[[5thp]] - hIG residues 170-366 + rhodocetin <br />
*IG α-2b
*IG α-2b
Line 87: Line 88:
*IG α-2 (CD49b) β
*IG α-2 (CD49b) β
 +
**[[5hj2]] - hIG I domain<br />
**[[1aox]] - hIG I domain (mutant) + Mg<br />
**[[1aox]] - hIG I domain (mutant) + Mg<br />
-
**[[1s4w]], [[1dpk]] - hIG cytoplasmic domain - NMR<BR />
+
**[[2k1a]] - hIG transmembrane domain – NMR<br />
-
**[[1dpq]] - hIG cytoplasmic domain (mutant) – NMR<br />
+
*IG α-2b β-3 (CD61)
*IG α-2b β-3 (CD61)
Line 125: Line 126:
**[[1m1x]] - hIG extracellular domain + Mn<br />
**[[1m1x]] - hIG extracellular domain + Mn<br />
**[[4mmx]], [[4mmy]], [[4mmz]] - hIG extracellular domain + Mn + fibronectin domain 10<br />
**[[4mmx]], [[4mmy]], [[4mmz]] - hIG extracellular domain + Mn + fibronectin domain 10<br />
-
**[[4o02]] - hIG extracellular domain + Mn + antibody<br />
+
**[[4o02]], [[6avu]], [[6avr]], [[6avq]] - hIG extracellular domain + antibody<br />
**[[1u8c]] – hIG psi domain + Ca<br />
**[[1u8c]] – hIG psi domain + Ca<br />
**[[1jv2]] - hIG I domain + platelet membrane glycoprotein IIIA + Ca<br />
**[[1jv2]] - hIG I domain + platelet membrane glycoprotein IIIA + Ca<br />
Line 135: Line 136:
**[[5ffg]] – hIG headpiece + Ca<br />
**[[5ffg]] – hIG headpiece + Ca<br />
**[[4um9]] – hIG headpiece (mutant) + Mg + transforming growth factor β 3<br />
**[[4um9]] – hIG headpiece (mutant) + Mg + transforming growth factor β 3<br />
 +
**[[5neu]], [[5net]], [[5ner]], [[5nem]] – hIG headpiece + foot-and-mouth virus – Cryo EM<br />
 +
**[[5ffo]] – hIG headpiece + TGF-beta-1<br />
*IG α-L
*IG α-L
Line 172: Line 175:
*IG β-2 (CD18)
*IG β-2 (CD18)
-
**[[2p26]], [[2p28]] – hIG phe2 + phe3 domains<br />
+
**[[2p26]], [[2p28]], [[5e6w]] – hIG phe2 + phe3 domains<br />
**[[1yuk]] – hIG chain A PSI domain + chain B I-EGF domain<br />
**[[1yuk]] – hIG chain A PSI domain + chain B I-EGF domain<br />

Revision as of 09:39, 22 July 2018

Structure of human integrin CD11a I domain dimer complex with Mg+2 (light green) and Cl- (dark green) ions (PDB entry 1zoo)

Drag the structure with the mouse to rotate

3D structures of integrin

Updated on 22-July-2018

References

  1. Humphries MJ. Integrin structure. Biochem Soc Trans. 2000;28(4):311-39. PMID:10961914
  2. Hillis GS, MacLeod AM. Integrins and disease. Clin Sci (Lond). 1996 Dec;91(6):639-50. PMID:8976799
  3. Larjava H, Koivisto L, Heino J, Hakkinen L. Integrins in periodontal disease. Exp Cell Res. 2014 Jul 15;325(2):104-10. doi: 10.1016/j.yexcr.2014.03.010. Epub, 2014 Mar 22. PMID:24662197 doi:http://dx.doi.org/10.1016/j.yexcr.2014.03.010
  4. Humphries MJ. Integrin structure. Biochem Soc Trans. 2000;28(4):311-39. PMID:10961914

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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