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GP1 of Lassa Virus

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<StructureSection load='4zjf' size='340' side='right' caption='4ZJF structure' scene=''>
<StructureSection load='4zjf' size='340' side='right' caption='4ZJF structure' scene=''>
==Importance==
==Importance==
-
Lassa virus is a devastating human pathogen that infects thousands of people each year primarily in West Africa, causing severe viral hemorrhagic fevers and significant mortality<ref>DOI 10.1128/JVI.00651-15</ref>.
+
Lassa virus is a notorious disease-causing agent primarily in West Africa that is able to spread to rodents, as well as humans. This deadly pathogen causes severe viral hemorrhagic fevers and significant mortality.
== Function ==
== Function ==
'''GP1''' (Glycoprotein 1) is the receptor binding domain of Lassa virus, an Old World [https://en.wikipedia.org/wiki/Arenavirus arenavirus].
'''GP1''' (Glycoprotein 1) is the receptor binding domain of Lassa virus, an Old World [https://en.wikipedia.org/wiki/Arenavirus arenavirus].

Revision as of 10:50, 22 June 2017

4ZJF structure

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References

You may include any references to papers as in: the use of JSmol in Proteopedia [2] or to the article describing Jmol [3] to the rescue.

  1. ↑ Cohen-Dvashi H, Cohen N, Israeli H, Diskin R. Molecular mechanism for LAMP1 recognition by Lassa Virus. J Virol. 2015 May 13. pii: JVI.00651-15. PMID:25972533 doi:http://dx.doi.org/10.1128/JVI.00651-15
  2. ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
  3. ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644

Proteopedia Page Contributors and Editors (what is this?)

Rebecca Holstein, Michal Harel

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