5nk4
From Proteopedia
(Difference between revisions)
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==Crystal Structure of Ephrin A2 (EphA2) Receptor Protein Kinase with Compound 2c== | ==Crystal Structure of Ephrin A2 (EphA2) Receptor Protein Kinase with Compound 2c== | ||
| - | <StructureSection load='5nk4' size='340' side='right' caption='[[5nk4]], [[Resolution|resolution]] 1.45Å' scene=''> | + | <StructureSection load='5nk4' size='340' side='right'caption='[[5nk4]], [[Resolution|resolution]] 1.45Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5nk4]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NK4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5NK4 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[5nk4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NK4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5NK4 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=90E:2-[[3-[[(4~{R})-3,3-bis(fluoranyl)piperidin-4-yl]carbamoyl]phenyl]amino]-~{N}-(2-chloranyl-6-methyl-phenyl)-1,3-thiazole-5-carboxamide'>90E</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=90E:2-[[3-[[(4~{R})-3,3-bis(fluoranyl)piperidin-4-yl]carbamoyl]phenyl]amino]-~{N}-(2-chloranyl-6-methyl-phenyl)-1,3-thiazole-5-carboxamide'>90E</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">EPHA2, ECK ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5nk4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nk4 OCA], [http://pdbe.org/5nk4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5nk4 RCSB], [http://www.ebi.ac.uk/pdbsum/5nk4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5nk4 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5nk4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nk4 OCA], [http://pdbe.org/5nk4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5nk4 RCSB], [http://www.ebi.ac.uk/pdbsum/5nk4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5nk4 ProSAT]</span></td></tr> | ||
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</div> | </div> | ||
<div class="pdbe-citations 5nk4" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 5nk4" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Ephrin receptor|Ephrin receptor]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Receptor protein-tyrosine kinase]] | [[Category: Receptor protein-tyrosine kinase]] | ||
| - | [[Category: | + | [[Category: Gande, S L]] |
| - | [[Category: | + | [[Category: Heinzlmeir, S]] |
| - | [[Category: | + | [[Category: Kudlinzki, D]] |
| - | [[Category: | + | [[Category: Kuester, B]] |
| - | [[Category: | + | [[Category: Linhard, V L]] |
| - | [[Category: | + | [[Category: Medard, G]] |
| - | [[Category: | + | [[Category: Saxena, K]] |
| - | [[Category: | + | [[Category: Schwalbe, H]] |
| - | [[Category: | + | [[Category: Witt, K]] |
[[Category: Complex]] | [[Category: Complex]] | ||
[[Category: Inhibitor]] | [[Category: Inhibitor]] | ||
[[Category: Protein tyrosine kinase]] | [[Category: Protein tyrosine kinase]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
Revision as of 06:03, 12 June 2019
Crystal Structure of Ephrin A2 (EphA2) Receptor Protein Kinase with Compound 2c
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