1w0i

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[[Image:1w0i.gif|left|200px]]
[[Image:1w0i.gif|left|200px]]
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{{Structure
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<!--
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|PDB= 1w0i |SIZE=350|CAPTION= <scene name='initialview01'>1w0i</scene>, resolution 2.10&Aring;
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The line below this paragraph, containing "STRUCTURE_1w0i", creates the "Structure Box" on the page.
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|SITE= <scene name='pdbsite=KAA:So4+Binding+Site+For+Chain+B'>KAA</scene>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-ketoacyl-acyl-carrier-protein_synthase_I Beta-ketoacyl-acyl-carrier-protein synthase I], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.41 2.3.1.41] </span>
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or leave the SCENE parameter empty for the default display.
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|GENE=
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-->
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|DOMAIN=
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{{STRUCTURE_1w0i| PDB=1w0i | SCENE= }}
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1w0i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w0i OCA], [http://www.ebi.ac.uk/pdbsum/1w0i PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1w0i RCSB]</span>
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}}
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'''ARABIDOPSIS THALIANA MITOCHONDRIAL KAS'''
'''ARABIDOPSIS THALIANA MITOCHONDRIAL KAS'''
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[[Category: Rasmussen, A V.]]
[[Category: Rasmussen, A V.]]
[[Category: Wettstein-Knowles, P Von.]]
[[Category: Wettstein-Knowles, P Von.]]
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[[Category: beta-ketoacyl-(acyl carrier protein) synthase]]
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[[Category: Condensing enzyme]]
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[[Category: condensing enzyme]]
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[[Category: Fatty acid elongation]]
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[[Category: fatty acid elongation]]
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[[Category: Lipid metabolism]]
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[[Category: lipid metabolism]]
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[[Category: Synthase]]
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[[Category: synthase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 12:59:41 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 00:29:27 2008''
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Revision as of 09:59, 3 May 2008

Image:1w0i.gif

Template:STRUCTURE 1w0i

ARABIDOPSIS THALIANA MITOCHONDRIAL KAS


Overview

Mitochondrial fatty acid synthesis is catalyzed by a dissociated fatty acid synthase similar to those of plant plastids and bacteria. The crystal structure of a mitochondrial beta-ketoacyl-[acyl carrier protein] synthase (mtKAS), namely that from Arabidopsis thaliana, has been determined for the first time. This enzyme accomplishes the vital condensation steps in constructing fatty acid carbon skeletons. The product profile of mtKAS is unusual in that C8 and C(14-16) fatty acyl chains predominate. An enzyme architecture that likely is the basis for the observed bimodal profile of mtKAS products can be derived from the shape of the acyl binding pocket.

About this Structure

1W0I is a Single protein structure of sequence from Arabidopsis thaliana. Full crystallographic information is available from OCA.

Reference

Structure of the mitochondrial beta-ketoacyl-[acyl carrier protein] synthase from Arabidopsis and its role in fatty acid synthesis., Olsen JG, Rasmussen AV, von Wettstein-Knowles P, Henriksen A, FEBS Lett. 2004 Nov 5;577(1-2):170-4. PMID:15527780 Page seeded by OCA on Sat May 3 12:59:41 2008

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