Alpha-lactalbumin

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<StructureSection load='1hml' size='350' side='right' caption='Human α-lactalbumin complex with sulfate, Zn+2 (grey) and Ca+2 (green) ions (PDB code [[1hml]]).' scene='46/468232/Cv/1'>
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<StructureSection load='1hml' size='350' side='right' caption='Human α-lactalbumin complex with sulfate, Zn+2 (grey) and Ca+2 (green) ions (PDB code [[1hml]]).' scene='46/468232/Cv/1' pspeed='8'>
== Function ==
== Function ==
'''Alpha-lactalbumin''' (LCA) is the albumin contained in milk and obtained from whey<ref>PMID:10818224</ref>. LCA is the regulatory subunit of the lactose synthase heterodimer which produces lactose by transferring galactose moieties to glucose.
'''Alpha-lactalbumin''' (LCA) is the albumin contained in milk and obtained from whey<ref>PMID:10818224</ref>. LCA is the regulatory subunit of the lactose synthase heterodimer which produces lactose by transferring galactose moieties to glucose.
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LCA is tested as a target for potential breast cancer vaccine. LCA is the major whey protein of cow and sheep milk. LCA is the target of testing for the presence of milk as an allergen.
LCA is tested as a target for potential breast cancer vaccine. LCA is the major whey protein of cow and sheep milk. LCA is the target of testing for the presence of milk as an allergen.
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== Structural highlights ==
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*<scene name='46/468232/Cv/2'>TextToBeDisplayed</scene>. Water molecules shown as red spheres.
</StructureSection>
</StructureSection>
== 3D Structures of α-lactalbumin ==
== 3D Structures of α-lactalbumin ==

Revision as of 09:46, 7 August 2017

Human α-lactalbumin complex with sulfate, Zn+2 (grey) and Ca+2 (green) ions (PDB code 1hml).

Drag the structure with the mouse to rotate

3D Structures of α-lactalbumin

Updated on 07-August-2017

References

  1. Permyakov EA, Berliner LJ. alpha-Lactalbumin: structure and function. FEBS Lett. 2000 May 19;473(3):269-74. PMID:10818224

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Michal Harel, Alexander Berchansky, Jaime Prilusky

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