2je3
From Proteopedia
(New page: 200px<br /> <applet load="2je3" size="450" color="white" frame="true" align="right" spinBox="true" caption="2je3, resolution 1.80Å" /> '''CYTOCHROME P460 FRO...) |
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==About this Structure== | ==About this Structure== | ||
| - | 2JE3 is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Nitrosomonas_europaea Nitrosomonas europaea]] with PO4 and HEC as [[http://en.wikipedia.org/wiki/ligands ligands]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2JE3 OCA]]. | + | 2JE3 is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Nitrosomonas_europaea Nitrosomonas europaea]] with PO4 and HEC as [[http://en.wikipedia.org/wiki/ligands ligands]]. Structure known Active Site: AC1. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2JE3 OCA]]. |
==Reference== | ==Reference== | ||
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[[Category: metal binding protein]] | [[Category: metal binding protein]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 11:09:02 2007'' |
Revision as of 09:04, 30 October 2007
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CYTOCHROME P460 FROM NITROSOMONAS EUROPAEA- PROBABLE PHYSIOLOGICAL FORM
Overview
We have determined the 1.8 A X-ray crystal structure of a monoheme c-type, cytochrome, cytochrome P460, from Nitrosomonas europea. The chromophore, possesses unusual spectral properties analogous to those of the catalytic, heme P460 of hydroxylamine oxidoreductase (HAO), the only known heme in, biology to withdraw electrons from an iron-coordinated substrate. The, analysis reveals a homodimeric structure and elucidates a new c-type, cytochrome fold that is predominantly beta-sheet. In addition to the two, cysteine thioether links to the porphyrin typical of c-type hemes, there, is a third proteinaceous link involving a conserved lysine. The covalent, bond is between the lysine side-chain nitrogen and the 13'-meso carbon of, the heme, which, following cross-link formation, is ... [(full description)]
About this Structure
2JE3 is a [Single protein] structure of sequence from [Nitrosomonas europaea] with PO4 and HEC as [ligands]. Structure known Active Site: AC1. Full crystallographic information is available from [OCA].
Reference
The Crystal Structure of Cytochrome P460 of Nitrosomonas europaea Reveals a Novel Cytochrome Fold and Heme-Protein Cross-link(,)., Pearson AR, Elmore BO, Yang C, Ferrara JD, Hooper AB, Wilmot CM, Biochemistry. 2007 Jul 17;46(28):8340-9. Epub 2007 Jun 21. PMID:17583915
Page seeded by OCA on Tue Oct 30 11:09:02 2007
