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5dia

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==PIM1 in complex with Cpd36 ((1S,3S)-N1-(6-(5-(pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridin-3-yl)pyridin-2-yl)cyclohexane-1,3-diamine)==
==PIM1 in complex with Cpd36 ((1S,3S)-N1-(6-(5-(pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridin-3-yl)pyridin-2-yl)cyclohexane-1,3-diamine)==
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<StructureSection load='5dia' size='340' side='right' caption='[[5dia]], [[Resolution|resolution]] 1.96&Aring;' scene=''>
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<StructureSection load='5dia' size='340' side='right'caption='[[5dia]], [[Resolution|resolution]] 1.96&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5dia]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DIA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5DIA FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5dia]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DIA OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5DIA FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5E6:(1S,3S)-N-{6-[5-(PYRIDIN-3-YL)-1H-PYRAZOLO[3,4-C]PYRIDIN-3-YL]PYRIDIN-2-YL}CYCLOHEXANE-1,3-DIAMINE'>5E6</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5E6:(1S,3S)-N-{6-[5-(PYRIDIN-3-YL)-1H-PYRAZOLO[3,4-C]PYRIDIN-3-YL]PYRIDIN-2-YL}CYCLOHEXANE-1,3-DIAMINE'>5E6</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5dgz|5dgz]], [[5dhj|5dhj]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5dgz|5dgz]], [[5dhj|5dhj]]</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5dia FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dia OCA], [http://pdbe.org/5dia PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5dia RCSB], [http://www.ebi.ac.uk/pdbsum/5dia PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5dia ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5dia FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dia OCA], [http://pdbe.org/5dia PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5dia RCSB], [http://www.ebi.ac.uk/pdbsum/5dia PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5dia ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Murray, J M]]
[[Category: Murray, J M]]

Revision as of 08:04, 8 April 2020

PIM1 in complex with Cpd36 ((1S,3S)-N1-(6-(5-(pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridin-3-yl)pyridin-2-yl)cyclohexane-1,3-diamine)

PDB ID 5dia

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