Nicotinic Acetylcholine Receptor
From Proteopedia
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[[4uxu]] – hAChR α-9 subunit extracellular domain + methyllycaconitine<br /> | [[4uxu]] – hAChR α-9 subunit extracellular domain + methyllycaconitine<br /> | ||
[[4uy2]] – hAChR α-9 subunit extracellular domain + α-bungarotoxin<br /> | [[4uy2]] – hAChR α-9 subunit extracellular domain + α-bungarotoxin<br /> | ||
| + | [[5hbt]] – hAChR α-1 subunit extracellular domain + α-bungarotoxin + antibody<br /> | ||
[[2qc1]] – AChR α subunit extracellular domain + α-bungarotoxin - mouse<br /> | [[2qc1]] – AChR α subunit extracellular domain + α-bungarotoxin - mouse<br /> | ||
[[3mra]] – TcAChR α subunit M3 transmembrane segment – ''Torpedo californica'' - NMR<br /> | [[3mra]] – TcAChR α subunit M3 transmembrane segment – ''Torpedo californica'' - NMR<br /> | ||
| - | [[2k58]] – AChR | + | [[2k58]] – AChR β-2 subunit M1 transmembrane segment - NMR<br /> |
| - | [[2k59]] – AChR | + | [[2k59]] – AChR β-2 subunit M2 transmembrane segment - NMR<br /> |
[[1oed]] – TmAChR pore – ''Torpedo marmorata'' – electron images<br /> | [[1oed]] – TmAChR pore – ''Torpedo marmorata'' – electron images<br /> | ||
[[2bg9]], [[4aq5]], [[4aq9]], [[4bog]], [[4boi]], [[4bon]], [[4boo]], [[4bor]], [[4bot]] – TmAChR – Cryo-EM<br /> | [[2bg9]], [[4aq5]], [[4aq9]], [[4bog]], [[4boi]], [[4bon]], [[4boo]], [[4bor]], [[4bot]] – TmAChR – Cryo-EM<br /> | ||
Revision as of 10:11, 22 August 2017
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3D Structures of nicotinic acetylcholine receptor
Updated on 22-August-2017
4d01 – hAChR α-9 subunit extracellular domain – human
4uxu – hAChR α-9 subunit extracellular domain + methyllycaconitine
4uy2 – hAChR α-9 subunit extracellular domain + α-bungarotoxin
5hbt – hAChR α-1 subunit extracellular domain + α-bungarotoxin + antibody
2qc1 – AChR α subunit extracellular domain + α-bungarotoxin - mouse
3mra – TcAChR α subunit M3 transmembrane segment – Torpedo californica - NMR
2k58 – AChR β-2 subunit M1 transmembrane segment - NMR
2k59 – AChR β-2 subunit M2 transmembrane segment - NMR
1oed – TmAChR pore – Torpedo marmorata – electron images
2bg9, 4aq5, 4aq9, 4bog, 4boi, 4bon, 4boo, 4bor, 4bot – TmAChR – Cryo-EM
References
1. Cholinesterase Inhibitors: Including Insecticides and Chemical Warfare Nerve Agents, Agency for Toxiz Substances and Disease Regulation accessed 5/2/14
2. Pierre-Jean Corringer and Jean-Pierre Changeux (2008) Nicotinic acetylcholine receptors. Scholarpedia, 3(1):3468.
3. Adcock C, Smith GR, Sansom MS. The nicotinic acetylcholine receptor: from molecular model to single-channel conductance. Eur Biophys J. 2000;29:29–37.
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Michal Harel, Joel L. Sussman, Alexander Berchansky, Alex Pennington
