Nucleoprotein
From Proteopedia
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| - | <StructureSection load='3mx2' size='400' side='right' caption='Nucleoprotein from Lassa virus trimer complex with TTP and Zn+2 ions (grey) [[3mx2]]' scene='46/461363/Cv/2'> | + | <StructureSection load='3mx2' size='400' side='right' caption='Nucleoprotein from Lassa virus trimer complex with TTP and Zn+2 ions (grey) [[3mx2]]' scene='46/461363/Cv/2' pspeed='8'> |
'''Nucleoproteins''' (NP) are proteins associated with DNA or RNA<ref>PMID:2203758</ref>. NPs which contain RNA are called '''ribonucleoproteins''' (RNPs). The NP RNA-recognition motif is named RRM.<br /> | '''Nucleoproteins''' (NP) are proteins associated with DNA or RNA<ref>PMID:2203758</ref>. NPs which contain RNA are called '''ribonucleoproteins''' (RNPs). The NP RNA-recognition motif is named RRM.<br /> | ||
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For details on '''heterogenous nuclear ribonucleoproteins''' see [[HnRNP A1]].<br /> | For details on '''heterogenous nuclear ribonucleoproteins''' see [[HnRNP A1]].<br /> | ||
For homology model and multiple sequence alignment see [[User:Michael Strong/H1N1/NP]] and [[User:Michael Strong/H1N1/NP/MSA]]. | For homology model and multiple sequence alignment see [[User:Michael Strong/H1N1/NP]] and [[User:Michael Strong/H1N1/NP/MSA]]. | ||
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| + | == Structural highlights == | ||
| + | *<scene name='46/461363/Cv/4'>TTP binding site</scene> in Nucleoprotein from Lassa virus ([[3mx2]]). Water molecules shown as red spheres. | ||
| + | *<scene name='46/461363/Cv/5'>Zn coordination site</scene>. | ||
</StructureSection> | </StructureSection> | ||
== 3D Structures of Nucleoprotein == | == 3D Structures of Nucleoprotein == | ||
Revision as of 11:02, 22 August 2017
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3D Structures of Nucleoprotein
Updated on 22-August-2017
References
- ↑ Echols H. Nucleoprotein structures initiating DNA replication, transcription, and site-specific recombination. J Biol Chem. 1990 Sep 5;265(25):14697-700. PMID:2203758
- ↑ Yong J, Wan L, Dreyfuss G. Why do cells need an assembly machine for RNA-protein complexes? Trends Cell Biol. 2004 May;14(5):226-32. PMID:15130578 doi:http://dx.doi.org/10.1016/j.tcb.2004.03.010
- ↑ He Y, Smith R. Nuclear functions of heterogeneous nuclear ribonucleoproteins A/B. Cell Mol Life Sci. 2009 Apr;66(7):1239-56. doi: 10.1007/s00018-008-8532-1. PMID:19099192 doi:http://dx.doi.org/10.1007/s00018-008-8532-1
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