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5jqo
From Proteopedia
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| - | | + | #REDIRECT [[6kyl]] This PDB entry is obsolete and replaced by 6kyl |
| - | ==Crystal Structure of Phosphatidic acid Transporter Ups1/Mdm35 in Complex with (2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate==
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| - | <StructureSection load='5jqo' size='340' side='right' caption='[[5jqo]], [[Resolution|resolution]] 3.55Å' scene=''>
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| - | == Structural highlights ==
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| - | <table><tr><td colspan='2'>[[5jqo]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JQO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5JQO FirstGlance]. <br>
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| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=44E:(2R)-3-(PHOSPHONOOXY)PROPANE-1,2-DIYL+DIHEXANOATE'>44E</scene></td></tr>
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| - | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5jql|5jql]], [[5jqm|5jqm]]</td></tr>
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| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5jqo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jqo OCA], [http://pdbe.org/5jqo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jqo RCSB], [http://www.ebi.ac.uk/pdbsum/5jqo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5jqo ProSAT]</span></td></tr>
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| - | </table>
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| - | == Function ==
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| - | [[http://www.uniprot.org/uniprot/MDM35_YEAST MDM35_YEAST]] Involved in mitochondrial distribution and morphology. Mediates the import of UPS1, UPS2 and UPS3, 3 atypical mitochondrial intermembrane space (IMS) proteins lacking the two major IMS-targeting signals, into the intermembrane space.<ref>PMID:11907266</ref> <ref>PMID:20622808</ref> <ref>PMID:20657548</ref> [[http://www.uniprot.org/uniprot/UPS1_YEAST UPS1_YEAST]] Required for maintenance of normal mitochondrial morphology as well as PCP1-dependent processing of MGM1. With UPS2, controls the level of cardiolipin in mitochondria. Cardiolipin is a unique phospholipid with four fatty acid chains and is present mainly in the mitochondrial inner membrane where it stabilizes the electron transport chain supercomplex between complexes III and IV through direct interaction of their subunits.<ref>PMID:16754953</ref> <ref>PMID:19221197</ref> <ref>PMID:19506038</ref> <ref>PMID:20622808</ref>
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| - | == References ==
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| - | <references/>
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| - | __TOC__
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| - | </StructureSection>
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| - | [[Category: Chan, K C]]
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| - | [[Category: Fan, J]]
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| - | [[Category: Lu, J]]
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| - | [[Category: Sun, F]]
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| - | [[Category: Zhai, Y]]
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| - | [[Category: Lipid transport]]
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| - | [[Category: Transport protein]]
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Current revision
- REDIRECT 6kyl This PDB entry is obsolete and replaced by 6kyl
