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Pre-mRNA-splicing factor

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**[[2do5]] – hPrp subunit 2 – NMR<BR />
**[[2do5]] – hPrp subunit 2 – NMR<BR />
**[[1x5t]] - hPrp subunit 4 – NMR<BR />
**[[1x5t]] - hPrp subunit 4 – NMR<BR />
-
**[[1x5u]] - hPrp subunit 4 RNA-binding domain – NMR<BR />
+
**[[5gvq]] - hPrp subunit 4 RNA-binding domain – NMR<BR />
*Pre-mRNA-splicing factor 8
*Pre-mRNA-splicing factor 8

Revision as of 18:54, 28 December 2017

Yeast pre-mRNA-splicing factor 8 (green) complex with AAR2 (cyan) (PDB entry 3zef)

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3D Structures of pre-mRNA splicing factors

Updated on 28-December-2017



References

  1. ↑ Misteli T, Spector DL. RNA polymerase II targets pre-mRNA splicing factors to transcription sites in vivo. Mol Cell. 1999 Jun;3(6):697-705. PMID:10394358
  2. ↑ McKie AB, McHale JC, Keen TJ, Tarttelin EE, Goliath R, van Lith-Verhoeven JJ, Greenberg J, Ramesar RS, Hoyng CB, Cremers FP, Mackey DA, Bhattacharya SS, Bird AC, Markham AF, Inglehearn CF. Mutations in the pre-mRNA splicing factor gene PRPC8 in autosomal dominant retinitis pigmentosa (RP13). Hum Mol Genet. 2001 Jul 15;10(15):1555-62. PMID:11468273

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Michal Harel, Alexander Berchansky, Joel L. Sussman

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