1wub
From Proteopedia
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'''Crystal structure of the polyisoprenoid-binding protein, TT1927b, from Thermus thermophilus HB8''' | '''Crystal structure of the polyisoprenoid-binding protein, TT1927b, from Thermus thermophilus HB8''' | ||
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==About this Structure== | ==About this Structure== | ||
| - | 1WUB is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. This structure supersedes the now removed PDB entry | + | 1WUB is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1uf6 1uf6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WUB OCA]. |
==Reference== | ==Reference== | ||
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[[Category: Terada, T.]] | [[Category: Terada, T.]] | ||
[[Category: Yokoyama, S.]] | [[Category: Yokoyama, S.]] | ||
| - | [[Category: | + | [[Category: Beta-barrel]] |
| - | [[Category: | + | [[Category: Riken structural genomics/proteomics initiative]] |
| - | [[Category: | + | [[Category: Rsgi]] |
| - | [[Category: | + | [[Category: Structural genomic]] |
| - | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 14:08:41 2008'' | |
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | |
Revision as of 11:08, 3 May 2008
Crystal structure of the polyisoprenoid-binding protein, TT1927b, from Thermus thermophilus HB8
Overview
The isoprenoid quinones exist widely among prokaryotes and eukaryotes. They play essential roles in respiratory electron transport and in controlling oxidative stress and gene regulation. In the isoprenoid quinone biosynthetic pathway, polyprenyl pyrophosphates are used as isoprenoid side-chain precursors. Here we report the crystal structure of a novel polyprenyl pyrophosphate binding protein, TT1927b, from Thermus thermophilus HB8, complexed with its ligand. This protein belongs to the YceI-like family in the Pfam database, and its sequence homologs are present in a broad range of bacteria and archaea. The structure consists of an extended, eight-stranded, antiparallel beta-barrel. In the hydrophobic pore of the barrel, the protein binds the polyisoprenoid chain by hydrophobic interactions. Its overall structure resembles the lipocalin fold, but there is no sequence homology between TT1927b and the lipocalin family of proteins.
About this Structure
1WUB is a Single protein structure of sequence from Thermus thermophilus. This structure supersedes the now removed PDB entry 1uf6. Full crystallographic information is available from OCA.
Reference
Crystal structure of a novel polyisoprenoid-binding protein from Thermus thermophilus HB8., Handa N, Terada T, Doi-Katayama Y, Hirota H, Tame JR, Park SY, Kuramitsu S, Shirouzu M, Yokoyama S, Protein Sci. 2005 Apr;14(4):1004-10. Epub 2005 Mar 1. PMID:15741337 Page seeded by OCA on Sat May 3 14:08:41 2008
Categories: Single protein | Thermus thermophilus | Doi-Katayama, Y. | Hamana, H. | Handa, N. | Hirota, H. | Idaka, M. | Ishizuka, Y. | Kuramitsu, S. | Park, S Y. | RSGI, RIKEN Structural Genomics/Proteomics Initiative. | Shirouzu, M. | Tame, J R.H. | Terada, T. | Yokoyama, S. | Beta-barrel | Riken structural genomics/proteomics initiative | Rsgi | Structural genomic
