5nxs
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of Human Pro-myostatin Precursor at 4.2 A Resolution with Experimental Phases from SeMet labelling== | |
| - | + | <StructureSection load='5nxs' size='340' side='right' caption='[[5nxs]], [[Resolution|resolution]] 4.19Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5nxs]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NXS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5NXS FirstGlance]. <br> | |
| - | + | </td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5nxs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nxs OCA], [http://pdbe.org/5nxs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5nxs RCSB], [http://www.ebi.ac.uk/pdbsum/5nxs PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5nxs ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Disease == | ||
| + | [[http://www.uniprot.org/uniprot/GDF8_HUMAN GDF8_HUMAN]] Myostatin-related muscle hypertrophy. The disease is caused by mutations affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/GDF8_HUMAN GDF8_HUMAN]] Acts specifically as a negative regulator of skeletal muscle growth. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Cotton, T R]] | ||
| + | [[Category: Fischer, G]] | ||
| + | [[Category: Hyvonen, M]] | ||
| + | [[Category: Cystine knot]] | ||
| + | [[Category: Growth factor]] | ||
| + | [[Category: Signaling protein]] | ||
| + | [[Category: Tgfbeta family]] | ||
Revision as of 06:49, 17 January 2018
Crystal Structure of Human Pro-myostatin Precursor at 4.2 A Resolution with Experimental Phases from SeMet labelling
| |||||||||||
