5oi2

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m (Protected "5oi2" [edit=sysop:move=sysop])
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'''Unreleased structure'''
 
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The entry 5oi2 is ON HOLD
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==Dissociation of biochemical and antiretroviral activities of Integrase-LEDGF Allosteric Inhibitors revealed by resistance of A125 polymorphic HIV-1==
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<StructureSection load='5oi2' size='340' side='right' caption='[[5oi2]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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Authors: Ruff, M., Benarous, R.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5oi2]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OI2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5OI2 FirstGlance]. <br>
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Description: Dissociation of biochemical and antiretroviral activities of Integrase-LEDGF Allosteric Inhibitors revealed by resistance of A125 polymorphic HIV-1
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9VN:(2~{S})-2-[4-(4,4-dimethylcyclohexen-1-yl)-2-methyl-5-pyridin-4-yl-thiophen-3-yl]-2-[(2-methylpropan-2-yl)oxy]ethanoic+acid'>9VN</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CAS:S-(DIMETHYLARSENIC)CYSTEINE'>CAS</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4lh4|4lh4]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5oi2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5oi2 OCA], [http://pdbe.org/5oi2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5oi2 RCSB], [http://www.ebi.ac.uk/pdbsum/5oi2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5oi2 ProSAT]</span></td></tr>
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</table>
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__TOC__
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</StructureSection>
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[[Category: Benarous, R]]
[[Category: Ruff, M]]
[[Category: Ruff, M]]
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[[Category: Benarous, R]]
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[[Category: Catalytic core domain]]
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[[Category: Hiv-1]]
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[[Category: Integrase]]
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[[Category: Viral protein]]

Revision as of 04:59, 8 March 2018

Dissociation of biochemical and antiretroviral activities of Integrase-LEDGF Allosteric Inhibitors revealed by resistance of A125 polymorphic HIV-1

5oi2, resolution 2.20Å

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