5oly
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==5-fluorotryptophan labeled beta-phosphoglucomutase in a closed conformation, monoclinic crystal form== | |
| - | + | <StructureSection load='5oly' size='340' side='right' caption='[[5oly]], [[Resolution|resolution]] 2.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5oly]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OLY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5OLY FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=G6P:ALPHA-D-GLUCOSE-6-PHOSPHATE'>G6P</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MGF:TRIFLUOROMAGNESATE'>MGF</scene></td></tr> | |
| - | [[Category: | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=FTR:FLUOROTRYPTOPHANE'>FTR</scene></td></tr> |
| - | [[Category: Bowler, M | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-phosphoglucomutase Beta-phosphoglucomutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.2.6 5.4.2.6] </span></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5oly FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5oly OCA], [http://pdbe.org/5oly PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5oly RCSB], [http://www.ebi.ac.uk/pdbsum/5oly PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5oly ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/PGMB_LACLA PGMB_LACLA]] Catalyzes the interconversion of D-glucose 1-phosphate (G1P) and D-glucose 6-phosphate (G6P), forming beta-D-glucose 1,6-(bis)phosphate (beta-G16P) as an intermediate. The beta-phosphoglucomutase (Beta-PGM) acts on the beta-C(1) anomer of G1P. Glucose or lactose are used in preference to maltose, which is only utilized after glucose or lactose has been exhausted. It plays a key role in the regulation of the flow of carbohydrate intermediates in glycolysis and the formation of the sugar nucleotide UDP-glucose.<ref>PMID:9084169</ref> <ref>PMID:15005616</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Beta-phosphoglucomutase]] | ||
| + | [[Category: Bowler, M W]] | ||
| + | [[Category: Velsen, J von]] | ||
| + | [[Category: 19f-nmr]] | ||
| + | [[Category: Isomerase]] | ||
| + | [[Category: Nmr labeling]] | ||
| + | [[Category: Phosphoryl transfer]] | ||
Revision as of 06:28, 1 November 2017
5-fluorotryptophan labeled beta-phosphoglucomutase in a closed conformation, monoclinic crystal form
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