5q8c

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m (Protected "5q8c" [edit=sysop:move=sysop])
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'''Unreleased structure'''
 
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The entry 5q8c is ON HOLD
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==PanDDA analysis group deposition -- Crystal Structure of DCLRE1A after initial refinement with no ligand modelled (structure 221)==
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<StructureSection load='5q8c' size='340' side='right' caption='[[5q8c]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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Authors: Newman, J.A., Aitkenhead, H., Lee, S.Y., Kupinska, K., Burgess-Brown, N., Tallon, R., Krojer, T., von Delft, F., Arrowsmith, C.H., Edwards, A., Bountra, C., Gileadi, O.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5q8c]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Q8C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5Q8C FirstGlance]. <br>
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Description: PanDDA analysis group deposition --Crystal Structure of DCLRE1A after initial refinement with no ligand modelled (structure 221)
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5q8c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5q8c OCA], [http://pdbe.org/5q8c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5q8c RCSB], [http://www.ebi.ac.uk/pdbsum/5q8c PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5q8c ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/DCR1A_HUMAN DCR1A_HUMAN]] May be required for DNA interstrand cross-link repair. Also required for checkpoint mediated cell cycle arrest in early prophase in response to mitotic spindle poisons.<ref>PMID:15542852</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Aitkenhead, H]]
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[[Category: Arrowsmith, C H]]
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[[Category: Bountra, C]]
[[Category: Burgess-Brown, N]]
[[Category: Burgess-Brown, N]]
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[[Category: Aitkenhead, H]]
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[[Category: Delft, F von]]
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[[Category: Edwards, A]]
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[[Category: Gileadi, O]]
[[Category: Krojer, T]]
[[Category: Krojer, T]]
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[[Category: Lee, S.Y]]
 
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[[Category: Bountra, C]]
 
[[Category: Kupinska, K]]
[[Category: Kupinska, K]]
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[[Category: Arrowsmith, C.H]]
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[[Category: Lee, S Y]]
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[[Category: Von Delft, F]]
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[[Category: Newman, J A]]
[[Category: Tallon, R]]
[[Category: Tallon, R]]
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[[Category: Gileadi, O]]
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[[Category: Hydrolase]]
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[[Category: Newman, J.A]]
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[[Category: Pandda]]
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[[Category: Edwards, A]]
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[[Category: Sgc - diamond i04-1 fragment screening]]
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[[Category: Xchemexplorer]]

Revision as of 21:34, 9 August 2018

PanDDA analysis group deposition -- Crystal Structure of DCLRE1A after initial refinement with no ligand modelled (structure 221)

5q8c, resolution 2.00Å

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OCA

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