5txt

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'''Unreleased structure'''
 
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The entry 5txt is ON HOLD until Paper Publication
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==Structure of asymmetric apo/holo ALAS dimer from S. cerevisiae==
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<StructureSection load='5txt' size='340' side='right' caption='[[5txt]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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Authors: Brown, B.L., Grant, R.A., Kardon, J.R., Sauer, R.T., Baker, T.A.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5txt]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TXT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5TXT FirstGlance]. <br>
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Description: Structure of asymmetric apo/holo ALAS dimer from S. cerevisiae
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PE3:3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL'>PE3</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene></td></tr>
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[[Category: Kardon, J.R]]
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5txr|5txr]]</td></tr>
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[[Category: Sauer, R.T]]
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/5-aminolevulinate_synthase 5-aminolevulinate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.37 2.3.1.37] </span></td></tr>
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[[Category: Brown, B.L]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5txt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5txt OCA], [http://pdbe.org/5txt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5txt RCSB], [http://www.ebi.ac.uk/pdbsum/5txt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5txt ProSAT]</span></td></tr>
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[[Category: Grant, R.A]]
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</table>
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[[Category: Baker, T.A]]
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== Function ==
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[[http://www.uniprot.org/uniprot/HEM1_YEAST HEM1_YEAST]] Catalyzes the synthesis of 5-aminolevulinate (ALA) from succinyl-CoA and glycine, the first and rate-limiting step in heme biosynthesis.<ref>PMID:6381051</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: 5-aminolevulinate synthase]]
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[[Category: Baker, T A]]
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[[Category: Brown, B L]]
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[[Category: Grant, R A]]
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[[Category: Kardon, J R]]
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[[Category: Sauer, R T]]
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[[Category: 5-aminolevulinic acid]]
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[[Category: Heme biosynthesis]]
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[[Category: Pyridoxal 5-phosphate]]
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[[Category: Transferase]]

Revision as of 06:30, 28 March 2018

Structure of asymmetric apo/holo ALAS dimer from S. cerevisiae

5txt, resolution 2.70Å

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