2jek

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(New page: 200px<br /> <applet load="2jek" size="450" color="white" frame="true" align="right" spinBox="true" caption="2jek, resolution 1.38&Aring;" /> '''CRYSTAL STRUCTURE O...)
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==About this Structure==
==About this Structure==
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2JEK is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]] with SO4 and GOL as [[http://en.wikipedia.org/wiki/ligands ligands]]. This structure superseeds the now removed PDB entry 2D2Y. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2JEK OCA]].
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2JEK is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]] with SO4 and GOL as [[http://en.wikipedia.org/wiki/ligands ligands]]. This structure superseeds the now removed PDB entry 2D2Y. Structure known Active Site: AC1. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2JEK OCA]].
==Reference==
==Reference==
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[[Category: unknown function]]
[[Category: unknown function]]
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Mon Oct 29 17:26:32 2007''
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 11:09:44 2007''

Revision as of 09:05, 30 October 2007

Image:2jek.gif

2jek, resolution 1.38Å

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CRYSTAL STRUCTURE OF THE CONSERVED HYPOTHETICAL PROTEIN RV1873 FROM MYCOBACTERIUM TUBERCULOSIS AT 1.38 A

Overview

The X-ray crystal structure of the gene product encoded by open reading, frame Rv1873 of Mycobacterium tuberculosis has been determined by single, isomorphous replacement with anomalous scattering (SIRAS) phasing, techniques at 1.38 A resolution from monoclinic crystals with unit-cell, parameters a = 33.44, b = 31.63, c = 53.19 A, beta = 90.8 degrees. The, 16.2 kDa Rv1873 is a monomer that adopts a primarily alpha-helical fold, with limited structural similarity to previously determined tertiary, structures. It has been annotated as a conserved hypothetical protein of, unknown function and is classified by the Clusters of Orthologous Groups, (COG) database as belonging to COG5579. The three-dimensional structure of, the Rv1873 gene product reveals limited similarity to a repeated motif, ... [(full description)]

About this Structure

2JEK is a [Single protein] structure of sequence from [Mycobacterium tuberculosis] with SO4 and GOL as [ligands]. This structure superseeds the now removed PDB entry 2D2Y. Structure known Active Site: AC1. Full crystallographic information is available from [OCA].

Reference

The molecular structure of Rv1873, a conserved hypothetical protein from Mycobacterium tuberculosis, at 1.38 A resolution., Garen CR, Cherney MM, Bergmann EM, James MN, Acta Crystallograph Sect F Struct Biol Cryst Commun. 2006 Dec 1;62(Pt, 12):1201-5. Epub 2006 Nov 30. PMID:17142896

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