5wpw
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of coconut allergen cocosin== | |
| + | <StructureSection load='5wpw' size='340' side='right' caption='[[5wpw]], [[Resolution|resolution]] 1.85Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5wpw]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WPW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5WPW FirstGlance]. <br> | ||
| + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5wpw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wpw OCA], [http://pdbe.org/5wpw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wpw RCSB], [http://www.ebi.ac.uk/pdbsum/5wpw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wpw ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Coconut (Cocos nucifera) is an important palm tree. Coconut fruit is widely consumed. The most abundant storage protein in coconut fruit is cocosin (a likely food allergen), which belongs to the 11S globulin family. Cocosin was crystallized near a century ago, but its structure remains unknown. By optimizing crystallization conditions and cryoprotectant solutions, we were able to obtain cocosin crystals that diffracted to 1.85 A. The cocosin gene was cloned from genomic DNA isolated from dry coconut tissue. The protein sequence deduced from the predicted cocosin coding sequence was used to guide model building and structure refinement. The structure of cocosin was determined for the first time, and it revealed a typical 11S globulin feature of a double layer doughnut-shaped hexamer. | ||
| - | + | Crystal Structure of Cocosin, A Potential Food Allergen from Coconut (Cocos nucifera).,Jin T, Wang C, Zhang C, Wang Y, Chen YW, Guo F, Howard A, Cao MJ, Fu TJ, McHugh TH, Zhang Y J Agric Food Chem. 2017 Aug 30;65(34):7560-7568. doi: 10.1021/acs.jafc.7b02252., Epub 2017 Jul 31. PMID:28712292<ref>PMID:28712292</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | + | </div> | |
| - | [[Category: Jin, T | + | <div class="pdbe-citations 5wpw" style="background-color:#fffaf0;"></div> |
| - | [[Category: Zhang, Y | + | == References == |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Jin, T]] | ||
| + | [[Category: Zhang, Y]] | ||
| + | [[Category: 11s globulin]] | ||
| + | [[Category: Allergen]] | ||
| + | [[Category: Seed storage protein]] | ||
Revision as of 06:57, 25 October 2017
Crystal structure of coconut allergen cocosin
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