5wwd
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of AtNUDX1== | |
| - | + | <StructureSection load='5wwd' size='340' side='right' caption='[[5wwd]], [[Resolution|resolution]] 1.39Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5wwd]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WWD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5WWD FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2ME:METHOXYETHANE'>2ME</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NH4:AMMONIUM+ION'>NH4</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5wwd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wwd OCA], [http://pdbe.org/5wwd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wwd RCSB], [http://www.ebi.ac.uk/pdbsum/5wwd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wwd ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/NUDT1_ARATH NUDT1_ARATH]] Mediates the hydrolysis of some nucleoside diphosphate derivatives. Its substrate specificity is unclear. In vitro, it can use NTP, dNTP, 8-oxo-GTP, 8-oxo-dGTP, dGTP, dATP, dTTP or dihydroneopterin triphosphate (DHNTP) as substrate. Has some NADH pyrophosphatase activity in vitro; however, such activity may not be relevant in vivo due to the high concentration of manganese used during the experiments. Plays an important role in protection against oxidative DNA and RNA damage by removing oxidatively damaged form of guanine.<ref>PMID:15611104</ref> <ref>PMID:15878881</ref> <ref>PMID:17804481</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Guan, Z]] | ||
| + | [[Category: Liu, J]] | ||
| + | [[Category: Yan, L]] | ||
[[Category: Yin, P]] | [[Category: Yin, P]] | ||
[[Category: Zou, T]] | [[Category: Zou, T]] | ||
| - | [[Category: | + | [[Category: Apo]] |
| - | [[Category: | + | [[Category: Arabidopsis thaliana]] |
| - | [[Category: | + | [[Category: Hydrolase]] |
| + | [[Category: Nudx1]] | ||
Revision as of 07:38, 15 November 2017
Crystal structure of AtNUDX1
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Categories: Guan, Z | Liu, J | Yan, L | Yin, P | Zou, T | Apo | Arabidopsis thaliana | Hydrolase | Nudx1
