5wwv
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of porcine kidney D-amino acid oxidase mutant (I230A/R283G)== | |
| - | + | <StructureSection load='5wwv' size='340' side='right' caption='[[5wwv]], [[Resolution|resolution]] 3.20Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5wwv]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WWV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5WWV FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=7V3:(S)-(4-chlorophenyl)-phenyl-methanamine'>7V3</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3wgt|3wgt]], [[5wx2|5wx2]]</td></tr> |
| - | [[Category: | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/D-amino-acid_oxidase D-amino-acid oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.4.3.3 1.4.3.3] </span></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5wwv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wwv OCA], [http://pdbe.org/5wwv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wwv RCSB], [http://www.ebi.ac.uk/pdbsum/5wwv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wwv ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/OXDA_PIG OXDA_PIG]] Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: D-amino-acid oxidase]] | ||
| + | [[Category: Asano, Y]] | ||
[[Category: Motojima, F]] | [[Category: Motojima, F]] | ||
| - | [[Category: Asano, Y]] | ||
[[Category: Ohno, A]] | [[Category: Ohno, A]] | ||
| + | [[Category: Yasukawa, K]] | ||
| + | [[Category: Fad-binding]] | ||
| + | [[Category: Oxidase]] | ||
| + | [[Category: Oxidoreductase]] | ||
Revision as of 06:56, 17 January 2018
Crystal structure of porcine kidney D-amino acid oxidase mutant (I230A/R283G)
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