1xp6

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
[[Image:1xp6.gif|left|200px]]
[[Image:1xp6.gif|left|200px]]
-
{{Structure
+
<!--
-
|PDB= 1xp6 |SIZE=350|CAPTION= <scene name='initialview01'>1xp6</scene>, resolution 1.70&Aring;
+
The line below this paragraph, containing "STRUCTURE_1xp6", creates the "Structure Box" on the page.
-
|SITE=
+
You may change the PDB parameter (which sets the PDB file loaded into the applet)
-
|LIGAND= <scene name='pdbligand=AIU:(2S,3R)-2-(4-{2-[(3S,4S)-3,4-DIMETHYLPYRROLIDIN-1-YL]ETHOXY}PHENYL)-3-(4-HYDROXYPHENYL)-2,3-DIHYDRO-1,4-BENZOXATHIIN-6-OL'>AIU</scene>
+
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-
|ACTIVITY=
+
or leave the SCENE parameter empty for the default display.
-
|GENE= ESR1, NR3A1, ESR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
+
-->
-
|DOMAIN=
+
{{STRUCTURE_1xp6| PDB=1xp6 | SCENE= }}
-
|RELATEDENTRY=[[1xp1|1XP1]], [[1xp9|1XP9]], [[1xpc|1XPC]]
+
-
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xp6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xp6 OCA], [http://www.ebi.ac.uk/pdbsum/1xp6 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1xp6 RCSB]</span>
+
-
}}
+
'''HUMAN ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH COMPOUND 16'''
'''HUMAN ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH COMPOUND 16'''
Line 27: Line 24:
[[Category: Fitzgerald, P M.D.]]
[[Category: Fitzgerald, P M.D.]]
[[Category: Sharma, N.]]
[[Category: Sharma, N.]]
-
[[Category: antagonist]]
+
[[Category: Antagonist]]
-
[[Category: er-alpha]]
+
[[Category: Er-alpha]]
-
[[Category: nuclear receptor]]
+
[[Category: Nuclear receptor]]
-
[[Category: transcription factor]]
+
[[Category: Transcription factor]]
-
 
+
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 15:19:26 2008''
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 00:52:41 2008''
+

Revision as of 12:19, 3 May 2008

Image:1xp6.gif

Template:STRUCTURE 1xp6

HUMAN ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH COMPOUND 16


Overview

A series of dihydrobenzoxathiin SERAMs with alkylated pyrrolidine side chains or alkylated linkers was prepared. Minor modifications in the side chain or linker resulted in significant effects on biological activity, especially in uterine tissue.

About this Structure

1XP6 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Estrogen receptor ligands. Part 9: Dihydrobenzoxathiin SERAMs with alkyl substituted pyrrolidine side chains and linkers., Blizzard TA, Dininno F, Morgan JD 2nd, Chen HY, Wu JY, Kim S, Chan W, Birzin ET, Yang YT, Pai LY, Fitzgerald PM, Sharma N, Li Y, Zhang Z, Hayes EC, Dasilva CA, Tang W, Rohrer SP, Schaeffer JM, Hammond ML, Bioorg Med Chem Lett. 2005 Jan 3;15(1):107-13. PMID:15582421 Page seeded by OCA on Sat May 3 15:19:26 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1xp6"
Personal tools