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5y41
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of LIGAND-BOUND NURR1-LBD== | |
| - | + | <StructureSection load='5y41' size='340' side='right' caption='[[5y41]], [[Resolution|resolution]] 2.05Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5y41]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Y41 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5Y41 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=RPG:(13E,15S)-15-hydroxy-9-oxoprosta-10,13-dien-1-oic+acid'>RPG</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5y41 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5y41 OCA], [http://pdbe.org/5y41 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5y41 RCSB], [http://www.ebi.ac.uk/pdbsum/5y41 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5y41 ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/NR4A2_HUMAN NR4A2_HUMAN]] Transcriptional regulator which is important for the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during development. It is crucial for expression of a set of genes such as SLC6A3, SLC18A2, TH and DRD2 which are essential for development of mdDA neurons (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Lescar, J]] | ||
[[Category: Sreekanth, R]] | [[Category: Sreekanth, R]] | ||
| - | [[Category: | + | [[Category: Yoon, H S]] |
| - | [[Category: | + | [[Category: Lbd]] |
| + | [[Category: Michael addition]] | ||
| + | [[Category: Nurr1]] | ||
| + | [[Category: Prostaglandin]] | ||
| + | [[Category: Transcription]] | ||
Revision as of 08:10, 26 December 2018
Crystal Structure of LIGAND-BOUND NURR1-LBD
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Categories: Lescar, J | Sreekanth, R | Yoon, H S | Lbd | Michael addition | Nurr1 | Prostaglandin | Transcription
