6ei6
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==CC2D1B coordinates ESRCT-III activity during the mitotic reformation of the nuclear envelope== | |
| - | + | <StructureSection load='6ei6' size='340' side='right' caption='[[6ei6]], [[Resolution|resolution]] 2.46Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6ei6]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6EI6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6EI6 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ei6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ei6 OCA], [http://pdbe.org/6ei6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ei6 RCSB], [http://www.ebi.ac.uk/pdbsum/6ei6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ei6 ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/C2D1_DROME C2D1_DROME]] Negative regulator of the Notch signaling pathway, acting to restrict the activity of Notch to the dorsoventral (D/V) boundary of the wing imaginal disk. Also causes negative regulation of Notch during vein, eye, and bristle development. Acts by targeting Notch for endosomal degradation or recycling.<ref>PMID:12648493</ref> <ref>PMID:17088062</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Caballe, A]] | ||
| + | [[Category: Carlton, J G]] | ||
| + | [[Category: Cuesta-Geijo, M A]] | ||
| + | [[Category: Macheboeuf, P]] | ||
| + | [[Category: Martinelli, N]] | ||
| + | [[Category: Miguet, N]] | ||
| + | [[Category: Olmos, Y]] | ||
| + | [[Category: Parnham, I M]] | ||
| + | [[Category: Ventimiglia, L N]] | ||
| + | [[Category: Weissehorn, W]] | ||
| + | [[Category: Martin-Serrano, J]] | ||
| + | [[Category: Cytosolic protein]] | ||
| + | [[Category: Escrt protein regulator]] | ||
| + | [[Category: Nuclear envelope reformation]] | ||
| + | [[Category: Polymerization]] | ||
Revision as of 08:09, 10 October 2018
CC2D1B coordinates ESRCT-III activity during the mitotic reformation of the nuclear envelope
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