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6ei8
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of human tRNA-dihydrouridine (20) synthase dsRBD F359A mutant== | |
| - | + | <StructureSection load='6ei8' size='340' side='right' caption='[[6ei8]], [[Resolution|resolution]] 2.25Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6ei8]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6EI8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6EI8 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ei8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ei8 OCA], [http://pdbe.org/6ei8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ei8 RCSB], [http://www.ebi.ac.uk/pdbsum/6ei8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ei8 ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/DUS2L_HUMAN DUS2L_HUMAN]] Dihydrouridine synthase. Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Negatively regulates the activation of EIF2AK2/PKR.<ref>PMID:15994936</ref> <ref>PMID:18096616</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Bou-Nader, C]] | ||
| + | [[Category: Hamdane, D]] | ||
| + | [[Category: Pecqueur, L]] | ||
| + | [[Category: Double-stranded rna-binding domain]] | ||
| + | [[Category: Rna binding protein]] | ||
Revision as of 08:09, 10 October 2018
Crystal structure of human tRNA-dihydrouridine (20) synthase dsRBD F359A mutant
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