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Actin

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Line 22: Line 22:
**[[3hbt]], [[2zwh]], [[1nwk]], [[1j6z]], [[3g37]], [[2y83]] – rAa – rabbit<br />
**[[3hbt]], [[2zwh]], [[1nwk]], [[1j6z]], [[3g37]], [[2y83]] – rAa – rabbit<br />
**[[2q1n]], [[2q31]], [[2a5x]], [[1rdw]], [[1rfq]], [[1lcu]] – rAa – dimer<br />
**[[2q1n]], [[2q31]], [[2a5x]], [[1rdw]], [[1rfq]], [[1lcu]] – rAa – dimer<br />
-
**[[3mfp]], [[4a7n]], [[3j8i]], [[3j8j]], [[3j8k]], [[3jbj]] – rAa – Cryo EM<br />
+
**[[3mfp]], [[4a7n]], [[3jbj]], [[6bnu]] – rAa + ADP – Cryo EM<br />
**[[2hmp]] – rAa – protease cleaved<br />
**[[2hmp]] – rAa – protease cleaved<br />
**[[2zwh]], [[2gwj]], [[2gwk]] – rAa-ATP<br />
**[[2zwh]], [[2gwj]], [[2gwk]] – rAa-ATP<br />
-
**[[3j8i]], [[3j8j]], [[3j8k]] – rAa + ADP – Cryo EM<br />
+
**[[3j8i]], [[3j8j]], [[3j8k]], [[6bno]], [[6avb]], [[6av9]], [[5mvy]], [[5mva]] – rAa + ADP – Cryo EM<br />
**[[3b5u]] – rAa filament – fiber diffraction<br />
**[[3b5u]] – rAa filament – fiber diffraction<br />
Line 37: Line 37:
**[[4z94]] - rAa+hGelsolin/tropomodulin/leiomodin<br />
**[[4z94]] - rAa+hGelsolin/tropomodulin/leiomodin<br />
**[[2ff6]] - rAa+DmCiboulot+hGelsolin <br />
**[[2ff6]] - rAa+DmCiboulot+hGelsolin <br />
-
**[[4cbu]] – Aa + gelsolin – ''Plasmodium falciparum''<br />
+
**[[4cbu]], [[5mvv]] – PfAa + gelsolin – ''Plasmodium falciparum''<br />
**[[4cbw]] – PbAa + gelsolin – ''Plasmodium berghei''<br />
**[[4cbw]] – PbAa + gelsolin – ''Plasmodium berghei''<br />
-
* α actin 1 complex
+
* α actin 1 complex with small molecule
 +
 
 +
**[[2q36]], [[1qz5]] – rAa+kabiramide C + ATP – dimer<br />
 +
**[[2vyp]] – rAa+myxobacterial rhizopodin + ATP<br />
 +
**[[1ijj]] - rAa+latrunculin A<br />
 +
**[[2fxu]] – rAa+bistramide A<br />
 +
**[[1wua]] – rAa+alpyronine A<br />
 +
**[[2asm]], [[2asp]] – rAa+reidispongiolide<br />
 +
**[[2aso]] – rAa+sphinxolide B<br />
 +
**[[1yxq]] – rAa+swinholide A<br />
 +
**[[4k41]], [[1qz6]], [[1s22]], [[4k42]], [[4k43]] - rAa+ macrolide<br />
 +
**[[1s22]] – rAa+ulapualide A<br />
 +
**[[1qz6]] – rAa+jaspisamide A<br />
 +
**[[3m6g]] – rAa+lobophorolide<br />
 +
**[[5ogw]] – PfAa + jasplakinolide + ADP – Cryo EM <br />
 +
 
 +
* α actin 1 complex with protein
**[[2w49]] – cAa +troponin C+ troponin T+ troponin I+ tropomyosin α-1 <br />
**[[2w49]] – cAa +troponin C+ troponin T+ troponin I+ tropomyosin α-1 <br />
Line 46: Line 62:
**[[3j8a]] - mAa + tropomyosin - mouse<br />
**[[3j8a]] - mAa + tropomyosin - mouse<br />
**[[4a7f]], [[4a7h]], [[4a7l]], [[5h53]], [[5kg8]] – rAa + tropomyosin α-1 + myosin heavy chain (mutant) – Cryo EM<br />
**[[4a7f]], [[4a7h]], [[4a7l]], [[5h53]], [[5kg8]] – rAa + tropomyosin α-1 + myosin heavy chain (mutant) – Cryo EM<br />
 +
**[[5nol]], [[5noj]], [[5nog]] – Aa + tropomyosin alpha-1 + ADP – pig - Cryo EM<br />
**[[5jlf]], [[3j8a]] – rAa + tropomyosin alpha-1 + ADP – Cryo EM<br />
**[[5jlf]], [[3j8a]] – rAa + tropomyosin alpha-1 + ADP – Cryo EM<br />
-
**[[2q36]], [[1qz5]] – rAa+kabiramide C – dimer<br />
+
**[[6c1h]], [[6c1g]], [[6c1d]] - rAa + myosin + calmodulin<br />
-
**[[2vyp]] – rAa+myxobacterial rhizopodin<br />
+
**[[6bnv]] - rAa + myosin + calmodulin – Cryo EM<br />
 +
**[[6bnw]], [[6bnp]] - rAa + myosin – Cryo EM<br />
 +
**[[6bnq]] - rAa + myosin + ADP – Cryo EM<br />
**[[2v51]], [[2v52]], [[2yje]], [[2yjf]] – rAa+mMKL/Myocardin-like protein <br />
**[[2v51]], [[2v52]], [[2yje]], [[2yjf]] – rAa+mMKL/Myocardin-like protein <br />
**[[2vcp]] – rAa+ neural wiskott-aldrich syndrome protein (hWASP) – human (h)<br />
**[[2vcp]] – rAa+ neural wiskott-aldrich syndrome protein (hWASP) – human (h)<br />
Line 67: Line 86:
**[[2q0r]] – rAa+pectenotoxin-2<br />
**[[2q0r]] – rAa+pectenotoxin-2<br />
**[[2q0u]] - rAa+pectenotoxin-2+latrunculin B<br />
**[[2q0u]] - rAa+pectenotoxin-2+latrunculin B<br />
-
**[[1ijj]] - rAa+latrunculin A<br />
 
-
**[[2fxu]] – rAa+bistramide A<br />
 
-
**[[1wua]] – rAa+alpyronine A<br />
 
-
**[[2asm]], [[2asp]] – rAa+reidispongiolide<br />
 
-
**[[2aso]] – rAa+sphinxolide B<br />
 
-
**[[1yxq]] – rAa+swinholide A<br />
 
**[[1y64]] – rAa+yBNI1 domain FH2 - yeast<br />
**[[1y64]] – rAa+yBNI1 domain FH2 - yeast<br />
**[[1sqk]] – rAa+DmCiboulot <br />
**[[1sqk]] – rAa+DmCiboulot <br />
**[[3sjh]], [[3u9d]], [[3u9z]] - rAa+DmCiboulot thymosin β-4 domain<br />
**[[3sjh]], [[3u9d]], [[3u9z]] - rAa+DmCiboulot thymosin β-4 domain<br />
-
**[[4k41]], [[1qz6]], [[1s22]], [[4k42]], [[4k43]] - rAa+ macrolide<br />
 
**[[3mn5]] – rAa+ DmSpire WH2 domain<br />
**[[3mn5]] – rAa+ DmSpire WH2 domain<br />
-
**[[1s22]] – rAa+ulapualide A<br />
 
-
**[[1qz6]] – rAa+jaspisamide A<br />
 
**[[1lot]], [[1kxp]], [[1ma9]] – rAa+hVitamin D binding protein<br />
**[[1lot]], [[1kxp]], [[1ma9]] – rAa+hVitamin D binding protein<br />
**[[3m1f]] – rAa+VOPL WH2 domain<br />
**[[3m1f]] – rAa+VOPL WH2 domain<br />
**[[3m3n]] – rAa+mN-WASP<br />
**[[3m3n]] – rAa+mN-WASP<br />
-
**[[3m6g]] – rAa+lobophorolide<br />
 
**[[3tpq]] – rAa + MAL RPEL domain<br />
**[[3tpq]] – rAa + MAL RPEL domain<br />
**[[3ue5]] – rAa + spire domain D<br />
**[[3ue5]] – rAa + spire domain D<br />
Line 102: Line 111:
**[[3byh]] – hAb+hFimbrin ABD2 – Cryo EM<br />
**[[3byh]] – hAb+hFimbrin ABD2 – Cryo EM<br />
**[[3j82]] – hAb + DNGR-1 - CryoEM <br />
**[[3j82]] – hAb + DNGR-1 - CryoEM <br />
 +
**[[6anu]] – hAb + spectrin – Cryo EM <br />
**[[2oan]] – cAb<br />
**[[2oan]] – cAb<br />
**[[3j0s]] – cAb + cofilin 2<br />
**[[3j0s]] – cAb + cofilin 2<br />
Line 134: Line 144:
* Actin 5C (A5C)
* Actin 5C (A5C)
-
**[[4rwt]] – DmA5C + leiomodin<br />
+
**[[4rwt]], [[5wfn]] – DmA5C + leiomodin<br />
**[[4efh]] – A + spire domains C,D – ''Acanthamoeba castellanii''
**[[4efh]] – A + spire domains C,D – ''Acanthamoeba castellanii''

Revision as of 09:41, 5 March 2018

Native G-actin with methyl-histidine complex with ATP, sulfate and Ca+2 ion (green) 3hbt

Drag the structure with the mouse to rotate

3D Structures of Actin

Updated on 05-March-2018

Reference

  1. ↑ Otterbein LR, Graceffa P, Dominguez R. The crystal structure of uncomplexed actin in the ADP state. Science. 2001 Jul 27;293(5530):708-11. PMID:11474115 doi:10.1126/science.1059700
  2. ↑ Wang H, Robinson RC, Burtnick LD. The structure of native G-actin. Cytoskeleton (Hoboken). 2010 Jul;67(7):456-65. PMID:20540085 doi:10.1002/cm.20458

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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